Ebola in Westafrika

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Birgitt
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Ebola-Fieber in Liberia

Beitrag von Birgitt »

The deadly Ebola virus has killed seven people in Liberia's capital, Monrovia, health officials have said. These are the first deaths reported in the city since the outbreak of the contagious virus in several West African states. Among the dead are a nurse and four people from the same household, including a baby, officials said.
Seven die in Monrovia Ebola outbreak
17.06.2014 - BBC

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Ebola-Fieber in Westafrika

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EBOLA VIRUS DISEASE - WEST AFRICA (66): LIBERIA (MONROVIA), SIERRA LEONE
************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this update:
[1] Liberia: Monrovia
[2] Sierra Leone


******
[1] Liberia: Monrovia
Date: 17 Jun 2014
Source: AP [edited]
http://bigstory.ap.org/article/liberian ... nked-ebola


Seven people believed to have the Ebola virus disease [EVD] have died in recent days in the 1st deaths reported in the Liberian capital [Monrovia] since the outbreak began, a health official said Tuesday [17 Jun 2014].

Deputy Health Minister Tolbert Nyenswah told The Associated Press that brings to 16 the number of people believed to have died from the virus in the West African country; 4 of the deaths were confirmed by tests to be EVD, he said.

The deaths, recorded since 8 Jun 2014, are worrying because no new cases had been confirmed in Liberia in about 2 months. Nyenswah said the new wave of cases was believed to have begun on 30 May [2014]. The ebolavirus, which causes severe bleeding and high fevers, has continued to ravage neighboring Guinea in that time and has spread to Sierra Leone. "The 1st phase of the epidemic was contained," said Nyenswah. "But because of proximity to Guinea and Sierra Leone, we did not declare the outbreak over." Other officials have previously downplayed the significance of the virus jumping borders, saying that it is to be expected since people travel and trade frequently across the borders of the 3 countries.

One of the 7 [recent] deaths was a woman who had recently traveled from an infected area in Sierra Leone and is believed to have passed the disease on to others in the house where she was staying in Monrovia. Fear of the disease, which has no known cure, appears to have helped its spread. There have been several reports of relatives taking sick loved ones out of isolation wards; that makes the work of stopping the disease's spread harder.

The outbreak appears to have begun in neighboring Guinea, where the vast majority of the cases and deaths have been recorded. Amara Jambai of Sierra Leone's Ministry of Health said Tuesday [17 Jun 2014] that the number of confirmed deaths from EVD in his country has risen to 20 in recent days.

The new deaths reported in Liberia and Sierra Leone would push the World Health Organization's death toll for the current outbreak to over 250.

There is no vaccine and no known cure for Ebola, which causes severe bleeding, although proper care can increase the survival rate.

[Byline: Jonathan Paye-Layleh, Clarence Roy-Macaulay]

--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

******
[2] Sierra Leone
Date: 16 Jun 2014
Source: Sierra Express Media [edited]
http://www.sierraexpressmedia.com/archives/68318


The update as of 16 Jun 2014 is as follows: Cases tested since March 2014 are 193 with 83 laboratory confirmed for Ebola, and 20 confirmed deaths. Total numbers of cases that have survived and been discharged from the Kenema Government hospital are 10. Contact tracing investigation continues.

Taking into consideration the magnitude of the growing case fatalities in the Kailahun district, the Ministry of Health, Line Ministries, and partners have intensified sensitization and health promotion as well as providing adequate manpower resources, Personal Protective Equipment and Universal Precaution Materials, which included masks, gowns, gloves and head gear. Also provided are chlorine, tricycle ambulances, 5000 disposable thermometers, tents, and solar lights at check points erected at strategic crossing points. In a bid to enhance effective communication between security personnel and health officials at check points and the health facilities, mobile phones have been provided per check points for efficient service delivery.

Meanwhile, the Ministry would like to re-emphasize that the erection of check points is not a measure to restrict movement of people but to avert the risk of contacting the Ebola disease and its possible spread from one place to another.

[Byline: Kadrie Koroma]

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[In Liberia, the presence of cases in the capital, Monrovia, with a population of approximately one million, will complicate contact tracing. In Conakry, which has twice that number population, the Guinean minister of health [said]: "At present, the rate of follow up of contacts identified in the country is 98 per cent for the Guekedou prefecture, 100 per cent for Macenta, and about 68 per cent for Conakry." See ProMED archive (64) below.

In Sierra Leone, the figures have been revised to show 55 more suspected cases, 30 more confirmed, and one additional death. - Mod.JW

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/46.]
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Ebola-Fieber in Westafrika

Beitrag von Birgitt »

The number of people killed by the deadly Ebola virus in West Africa has risen to 337, the World Health Organization (WHO) has said. Fourteen deaths and 47 new cases were reported across the region over the last week, it added. Guinea is worst-affected with 264 Ebola-related deaths. In Sierra Leone, there have been 49 deaths and in Liberia 24, the WHO said.
Ebola deaths pass 300 in West Africa - WHO
18.06.2014 - BBC

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Ebola-Fieber in Westafrika

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EBOLA VIRUS DISEASE - WEST AFRICA (67): WHO UPDATE, LIBERIA, SIERRA LEONE
*************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this update:
[1] Ebola virus disease, West Africa - WHO update
[2] Liberia: Foya
[3] Liberia: Voinjama
[4] Sierra Leone: Kailahun
[5] Sierra Leone: misinformation


******
[1] Ebola virus disease, West Africa - update
Date: 18 Jun 2014
Source: WHO Disease Outbreak News [edited]
http://who.int/csr/don/2014_06_18_ebola/en


Guinea
--------
Between 14 and 16 Jun 2014, a total of 7 new cases and 5 new deaths were reported from Gueckedou (4 cases and 5 deaths) and Boffa (3 cases and 0 deaths). This brings the cumulative number of cases and deaths reported from Guinea to 398 (254 confirmed, 88 probable and 56 suspected) [including] 264 deaths. [CFR (case fatality rate) 66 percent. - Mod.JW]

The geographical distribution of these cases and deaths is as follows: Conakry, 70 cases and 33 deaths; Gueckedou, 224 cases and 173 deaths [apparent CFR 77 percent. - Mod.JW]; Macenta, 41 cases and 28 deaths; Dabola, 4 cases and 4 deaths; Kissidougou, 8 cases and 5 deaths; Dinguiraye, 1 case and 1 death; Telimele, 30 cases and 9 deaths; Bofa, 19 cases and 10 deaths; and Kouroussa, 1 case and 1 death.

24 patients are currently in EVD Treatment Centres: Conakry, 6; Gueckedou, 9; Telimele, 3; and Boffa, 6.

The number of contacts currently being followed-up countrywide is 1258 and distributed as follows: Conakry, 252; Gueckedou, 529; Macenta, 52; Telimele, 118; Dubreka, 118; and Boffa, 189. So far, 69.4 percent (2848 contacts being followed-up out of 4106 contacts registered since the beginning of the outbreak) have completed the mandatory 21-day observation period.

Sierra Leone
------------
Between 15 and 17 Jun 2014, a total of 31 new cases and 4 new deaths were reported from Kailahun (29 cases and 4 deaths), Kono (1 case), and Western (1 case). This brings the cumulative number of cases and deaths reported from Sierra Leone to 97 (92 confirmed, 3 probable, and 2 suspected) and 49 deaths [apparent CFR 51 percent. - Mod.JW].

The geographical distribution of these cases and deaths is as follows: Kailahun, 92 cases and 46 deaths; Kambia, 1 case and 0 deaths; Port Loko, 2 cases and 1 death; Kono, 1 case and 0 deaths; and Western, 1 case and 1 death.

33 patients are currently in the EVD Treatment Centre in Kenema.

The number of contacts currently being followed-up countrywide is 37 from Kailahun. Contact listing is continuing in Kailahun, Kambia, and Port Loko.

Liberia
---------
Between 11 and 16 Jun 2014, a total of 9 new cases and 5 new deaths were reported from Lofa (6 cases and 0 deaths) and Montserrado (3 cases and 5 deaths). This brings the cumulative number of cases and deaths reported from Liberia to 33 (18 confirmed, 8 probable, and 7 suspected) and 24 deaths [ CFR 73 percent, but numbers are small. - Mods.JW/MPP].

The geographical distribution of these cases and deaths is as follows: Lofa, 21 cases and 14 deaths; Montserrado, 8 cases and 8 deaths; Margibi, 2 cases and 2 deaths; and Nimba, 2 cases and 0 deaths.

Five patients are currently in EVD Treatment Centres in Lofa.

The number of contacts currently being followed-up countrywide is 108 and distributed as follows: Lofa, 95 and Montserrado, 13. Thus far, 41.5 percent (108 contacts being followed-up out of 260 contacts registered since the beginning of the outbreak) have completed the mandatory 21-day observation period.

WHO response
-------------
Following the confirmation of new cases and deaths in new areas in Guinea, Liberia, and Sierra Leone, WHO and its partners continue to provide the necessary technical expertise to the Ministries of Health to stop community and health facility transmission of the virus. A high-level WHO mission was conducted in Guinea to assess the overall response to EVD and propose a strategic approach to control the outbreak. Among other actions, this includes high-level advocacy with the governments of the 3 affected countries to enhance coordination and communication at all national, provincial, and district levels.

WHO is also closely supporting the Ministries of Health in addressing community resistance that is emerging in some areas; deploying additional experts in the various specialties (epidemiology, social mobilization, case management, and logistics among others); and enhancing cross-border collaboration. The next cross-border meeting between the 3 countries is planned for 23 Jun 2014.

WHO does not recommend any travel or trade restrictions be applied to Guinea, Liberia, or Sierra Leone based on the current information available for this event.

This update has also been posted on the regional website of the WHO African Regional Office.

--
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[The fact that so many of the contacts have completed their 21-day observation period without falling ill indicates that their contact was not close enough to be dangerous. After this epidemic has ended, it would be important for future reference to test a sample of known contacts for evidence of sub-clinical infection and gather epidemiological information on the details of their contact. - Mod.JW]

******
[2] Liberia: Foya
Date: 16 Jun 2014
Source: APA [edited]
http://en.starafrica.com/news/3-ebola-c ... trict.html


The Health Officer of Lofa County, Dr. Aaron Kollie, has reported a fresh outbreak of the Ebola virus disease (EVD) in Foya district in northern Lofa County. Dr. Kollie told reporters in a telephone interview from Voinjama Monday [16 Jun 2014] that 3 new cases of EVD were recorded in Foya district over the past few days. He said one of the 3 cases has been confirmed, while the other 2, which have been classified as suspected cases, are undergoing laboratory tests.

Dr. Kollie pointed out that the 2 suspected cases have been quarantined under the watchful eyes of health practitioners of Foya district, while the positive EVD patient is on supportive treatment at the Burma Health Center in Foya. He attributed the fresh outbreak of the EVD in the county to cross-border movements between Liberia and Sierra Leone, where there is presently an outbreak of the virus, as well as Guinea, from where the earlier cases are reported to have emanated.

--
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******
[3] Liberia: Voinjama
Date: 18 Jun 2014
Source: APA [edited]
http://en.starafrica.com/news/new-ebola ... beria.html


Reports from Liberia's northern provincial city of Voinjama on Tuesday [17 Jun 2014] said a fresh outbreak of the deadly ebolavirus erupted there killing one person. The report quotes the Director of the Community Health Department in Voinjama, Lofa County, Edmund Esiah, as saying that 9 cases of the virus have been discovered at the Tellewoyan Hospital in Voinjama in the past few days.

Voinjama lies about 35 km from Foya, where another outbreak was reported Monday [16 Jun 2014, see previous report].

According to Director Esiah, 6 cases have been confirmed to be EVD, while the remaining 3 are all suspected cases awaiting laboratory confirmation. The dead victim, a 45-year-old [woman] is said to have traveled from Sierra Leone to seek treatment at the Tellewoyan Memorial Hospital in Voinjama City, where she subsequently died. The other victims have been quarantined.

--
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[Yet another cross-border transmission; this epidemic is extremely difficult to contain given free cross-border movement, which is impractical to try to stop. - Mod.JW]

******
[4] Sierra Leone: Kailahun
Date: 18 Jun 2014
Source: Cocorioko Newspaper [edited]
http://www.cocorioko.net/?p=56281


Health and Sanitation Minister Miatta Kargbo has described the outbreak of the killer Ebola virus disease (EVD) as another war that calls for the attention of every Sierra Leonean including Parliamentarians. Presenting the current status of the outbreak in the Well of Parliament, Madam Kargbo reiterated the commitment of the government and partners to contain the disease, describing the situation as a natural war that needs the moral support and responsibility of all well-meaning citizens of Sierra Leone.

The number of cases tested since March 2014 was slated at 193, confirmed cases 83, 20 deaths [CFR 10 percent. - Mod.JW] and 10 survivors as of 16 Jun 2014.

The Minister lauded the sacrifices made by health professionals, pointing out that in the process of saving the lives of other people, some passed away, a tragedy the Minister described as pathetic in the course of saving lives.

She denied claims of health workers abandoning their duty stations and enumerated instances where her staff worked under threat and crisis they could not stand due to community resistance in giving the necessary cooperation in managing the situation for referrals and treatment.

Commenting on the Kailahun situation, Madam Kargbo said: "Before now, Kailahun had 14 Surveillance Officers, but with the current trend, 300 volunteers have been recruited, bringing the number to 314 to enhance effective surveillance systems." Apart from the sensitization of Parliamentarians in the wake of the EVD outbreak in Guinea, Religious Leaders, Tribal Heads in the Western Area, [Motor] Bike Riders, the Motor Drivers Union, Traders, Paramount Chiefs and Media Practitioners have been sensitized and given orientation to help create the necessary awareness and education on the prevention of the disease.

The Minister spoke on the closure of schools in Kailahun and the risk of children contacting the disease, pointing out that the continuity of schooling is a risk, whilst the closure is a life-saving intervention.

Some of the challenges and lessons learnt, the Minister said, include negative press reports that could be disastrous, strong resistance from communities, escapees from treatment and observation units, total support for nationwide awareness raising campaigns, and the resources for health promotion and logistics for case management.

The Parliamentarians described some utterances in some radio stations and newspapers as disastrous to the fight to contain the disease and reiterated their total commitment and willingness to collaborate with the Ministry, its partners and Inter-Ministerial Committee to make the necessary impact.

The Parliamentarians in their contributions lauded the Ministry for the hard work since the outbreak in Guinea, and pledged to go to their various constituencies to sensitize their people. They call on all and sundry to put aside partisan, regionalism noting that the current crisis is a core task for Sierra Leoneans.

--
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******
[5] Sierra Leone: misinformation
Date: 16 Jun 2014
Source: Sierra Express Media [excerpted, edited]
http://www.sierraexpressmedia.com/archives/68298


The regional treasurer of the Sierra Leone Commercial Motor Bike Riders Union eastern region, Mohamed Sheriff, said [on 16 Jun 2014] that one of the ways of transferring ebolavirus is through the exchange of helmets by passengers and called on the authorities to stop the use of helmets at the moment, since the virus can be transferred through body contact [see comment below].

--
Communicated by:
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[Transmission could only occur if blood or vomit had contaminated the helmet. Banning their use is likely to add more deaths from head injuries in accidents than a ban could ever prevent from EVD.

There seem to be some conflicting figures for cases and deaths in these reports, but as WHO reminds us, this is an evolving situation in which numbers are subject to revision.

The misinformation reported above shows that there is still some way to go to inform the public of risk behaviors leading to transmission. - Mod.JW

HealthMap/ProMED-mail maps can be accessed at: http://healthmap.org/promed/p/54 and http://healthmap.org/promed/p/46.]
Hazi
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Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von Hazi »

Puh, jetzt muss ich doch mal was deutsches einstellen. Ganz schön anstrengend alles in englisch.

Dieser Link von April 14 ging noch von einer Analyse aus, die eine langsamen Eindämmung von Ebola sah
http://www.aerztezeitung.de/medizin/kra ... rueck.html

Heute sind aus den 121 Toten schon 337 geworden, was die Analyse von April wohl nicht voraus sah
http://www.rp-online.de/panorama/auslan ... -1.4323335
Astrid Därr
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Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von Astrid Därr »

Es wird offenbar immer schlimmer… :cry:

Spiegel Online heute: Warnung von Ärzte ohne Grenzen: Ebola-Epidemie in Westafrika "außer Kontrolle"
http://www.spiegel.de/wissenschaft/medi ... 76535.html
marylin
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Registriert: Do 29. Nov 2012, 10:56

Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von marylin »

Meiner Meinung hatte Westafrika bisher auch viel Glück- dadurch daß die Menschen dort verhältnismässig wenig reisen und eigentlich vor Ort gebunden sind, breitet sich eine Seuche langsamer aus. Allerdings kann der Erregen natürlich auch besser mutieren, wenn er lange "im Menschen" bleibt und übertragen w ird.
Sollte auch nur der erste Fall in europa auftreten, würde die Verbreitung, und damit die Zahl der Ansteckungen immens schneller steigen.
Leider konnte ich bisher noch nichts drüber lesen, daß z.B. auf Flughäfen alle Reisenden aus Westafrika auf Ebola getetstet wurden...
DAS sollte doch gemacht werden oder?
Auch innerafrikanisch wird ja untersucht- wenn auch nicht flächendeckend.
Hazi
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Registriert: Di 29. Apr 2014, 20:04

Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von Hazi »

Es kommen ja viele Flüchtlinge aus Westafrika nach Europa -Italien u.a.-.
Noch wird geschrieben, dass Europa vor Ebola gefeit ist.
Von April 14
http://www.t-online.de/nachrichten/ausl ... uropa.html
Menschen kommen nicht nur mit Flugzeugen nach Europa.
Im Grunde ist es nur eine Frage der Zeit, bis da mal was nach Europa einschleppt wird. Die Inkubationszeit soll bis 21 Tage betragen.
http://www.bueger.de/prima/khtext/Ebola-Fieber.htm

Selbst wenn der Hauptinfizierte in der Wüste sein Leben lässt, könnte er schon jemand anderen infiziert haben. Ich glaube kaum, dass alle Flüchtlinge nach anlanden auf verschiedene Viren untersucht werden. Zeitlich überhaupt nicht möglich.
Dann liest man immer nur von Heimkehrern, die aus dem Gebiet auf Flughäfen ankommen u. untersucht werden.
Die Welt ist sehr klein geworden. Afrika u. andere Länder sind nicht weit weit weg, sondern direkt nebenan.
marylin
Beiträge: 870
Registriert: Do 29. Nov 2012, 10:56

Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von marylin »

Ich meinte schon durchaus besonders auch die Europäer-
Schliesslich kehren die in häufigen Fällen eben INNERHALB der 21 tg Inkubationszeit zurück- natürlich MIT dem Flugzeug.
Dann kommt hinzu, daß man bei Bleichgesichtern bei "Unwohlsein" nicht gleich auf Ebola tippen wird....
Auch wird der Erkrankte nicht zu Hause bleiben, sondern fröhlich die MitarbeiterINNEN anstecken (passiert ja auch so schon oft genug- Stichwort Angst um den Arbeitsplatz)
Also DAS sehe ich als größere Gefahr....
Sagen wir: Bei jemandem aus Guinea- läuten die Alarmglocken lauter.
Hazi
Beiträge: 250
Registriert: Di 29. Apr 2014, 20:04

Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von Hazi »

@marylin
Mein Posting war nicht direkt auf dein Posting bezogen, sondern allgemein. Deshalb hatte ich die Link gesetzt.
Sicher werden die Flüchtlinge besonders beobachtet, aber mittelerweile hatten doch schon Menschen mit ihnen Kontakt, sind nach Hause gegangen, treffen andere Menschen ihrer Umgebung usw.
Sollte Ebola nach Europa eingeschleppt werden, könnte ich mir denken, dass die Flüchtlinge nicht mehr gerettet, sondern nach Afrika zurück eskortiert werden.
marylin
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Registriert: Do 29. Nov 2012, 10:56

Re: Ebola-Fieber in Guinea, Liberia und Sierra Leone

Beitrag von marylin »

Allein es würde uns nicht helfen, denn zurückgeschickte Flüchtlinge können die Seuche nicht bekämpfen.
Das mag zwar kostengünstig und vor allem werbewirksam sein- ist aber eben nicht zielgerichtet

Das würde nämlich heißen, das es keine Europäer gäbe, die das Virus in sich tragen.
Dies wäre nicht nu rassitsich, sonder aussergwöhnlich dumm.

DAS ist doch die eigentliche Gefahr, daß wir
a) denken Ebola an der Hautfarbe ausmachen zu können
b) aus Geldmangel nicht einfach jeden aus Afrika zurückgekehrten im Eingangsland zu untersuchen
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Ebola-Fieber in Liberia

Beitrag von Birgitt »

EBOLA VIRUS DISEASE - WEST AFRICA (68): LIBERIA, ONE HEALTH APPROACH
********************************************************************
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ProMED-mail is a program of the
International Society for Infectious Diseases
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In this posting:
[1] Liberia: UNICEF SitRep No. 25
[2] Liberia: hospital closure
[3] One Health approach needed


******
[1] Liberia: UNICEF SitRep No. 25
Date: Wed 18 Jun 2014
Source: ReliefWeb [edited]
http://www.static.reliefweb.int/sites/r ... ne2014.pdf


Update on Ebola outbreak No. 2*
-------------------------------
Since the last SitRep [No. 24, 17 Jun 2014], 4 new suspected cases were reported in Foya, Lofa County [Liberia]. Samples were taken from all 4 patients and were sent to the lab in Gueckedou, Guinea, for testing.

The total number of suspected, probable and confirmed EVD cases reported during the 2nd outbreak now stands at 26, including 18 cases in Lofa County and 8 cases in Montserrado County. The exact breakdown of cases is as follows:
- 8 suspected cases, all from Lofa County;
- 6 probable cases, including 2 from Lofa County and 4 from Montserrado County;
- 12 confirmed cases, including 8 from Lofa County and 4 from Montserrado County.

The total number of Ebola-related deaths still stands at 16, including 8 of the 18 patients in Lofa County and all 8 patients in Montserrado County. The latter includes the 1st child fatality connected to Ebola in Liberia.

The case fatality rate for this outbreak is over 60 per cent (16/26 cases). This includes deaths in 8/12 confirmed cases and all 6 probable cases.

The cumulative number of Ebola cases from both the 1st and 2nd outbreaks is being reviewed, as some cases from the 1st outbreak appear to have been discarded out upon deeper analysis.

Foya, Lofa County, and New Kru Town, Montserrado County, remain the epicentres of this EVD outbreak.

*The index patient for Outbreak No. 2 was admitted into Foya Borma Hospital in Lofa County on 23 May [2014], but her case was not officially reported by the MoHSW [Ministry of Health and Social Welfare] until 29 May [2014]. The Ministry is therefore considering 29 May [2014] its starting point for tracking the 2nd outbreak. Similarly, the 1st confirmed case of Ebola in Montserrado County was reported in New Kru Town on 12 Jun [2014], although the onset of symptoms in the patient likely predated this. Unless otherwise stated, all figures reflect totals for the 2nd outbreak of Ebola, which began on 29 May [2014].

--
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[Liberia considers itself now suffering from a 2nd outbreak. - Mod.JW]

******
[2] Liberia: hospital closure
Date: Wed 18 Jun 2014
Source: AllAfrica, FrontPageAfrica report [edited]
http://allafrica.com/stories/201406181674.html


"It was unfortunate; a nurse died from Ebola. She came down with the virus, we do not know where it came from, but you know Liberia has been having cases of Ebola," said Dominic W. Rennie, Administrator, Redemption Hospital, New Kru Town, Monrovia. On a sunny Tuesday afternoon [17 Jun 2014] the scene at a normally busy Redemption Hospital is eerie and quiet, the patient waiting area is empty and the drop of a pin can easily be heard. The hospital seems like a church during weekdays where the congregation only gathers on Sundays.

Though not officially shut down, the hospital is not taking patients, and many of the nurses and health workers cannot be found at the facility. FrontPageAfrica [FPA] later learned from a reliable source at the hospital that many of the nurses decided to boycott work due to fear for their lives, as a result of the death of a nurse last weekend [14-15 Jun 2014] who worked at the facility.

"The nurses did not come today because of the other nurse's death from Ebola. Even I did not come for 2 days because I was afraid," said the source that cautioned FPA reporters not to touch anything [and to] be careful how they move about the hospital.

A resident of Jamaica Road who came to seek medical treatment at the hospital, which is the only government referral hospital in the area, was turned away after the woman accompanying him told the security guard at the entrance of the facility that she had brought him for urgent medical attention as he could hardly stand.

"The hospital closed, we not accepting patients here. All the nurses gone home," said the guard who barricaded himself behind the small entrance that looked like an iron cage. The man, who could hardly walk, struggled to sit near the entrance of the facility; after hearing what the security guard said, his jaw dropped and he did not know what to say or do. "I only came here to treat myself, but the security at the gate did not allow me to enter, and this is the 1st time for this thing to happen to me since I have been taking treatment here," he said in frustration. The patient, who said he had nowhere else to go, as he had already come a far distance from where he lived, said people in his community had been talking about EVD [Ebola virus disease] in New Kru Town but he was confused about it.

"I do not know whether it is the Ebola or not because the people at Redemption are not telling us why we should not enter the hospital. I [have] been there about 3 times and they cannot allow me in," he said. "I have been hearing about this Ebola business from people in my community, that it is in New Kru Town; but I do not know where they are getting this story from, I do not know whether people are leaving New Kru Town."

[Byline: Wade C. L. Williams]

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[A sad story of lack of communication to hospital staff about how to take precautions when treating the disease.

See "A Liberian woman walks past the Redemption Hospital where a nurse reportedly died of Ebola virus in Monrovia, Liberia." Photograph: Ahmed Jallanzo/EPA. http://www.theguardian.com/global-devel ... p-epidemic. - Mod.JW]

******
[3] One Health approach needed
Date: Thu 19 Jun 2014
Source: The Guardian [edited]
http://www.theguardian.com/global-devel ... p-epidemic


Tackling the Ebola virus disease epidemic in West Africa: why we need a holistic approach
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Immediate medical action is not enough to manage the disease. We need cross-sector collaboration and integrated research.

As the death toll from Ebola virus disease [EVD] in West Africa continues to rise, there is a growing awareness of the threat of diseases transmitted from animals to people. EVD, a hemorrhagic fever that causes uncontrolled bleeding, is dramatic in its manifestation and has a case fatality rate of up to 90 percent. Its emergence can be sudden and unexplained and, as the recent crisis shows, it can spread across communities and borders with alarming speed.

What the outbreak confirms is that if animal transmitted diseases such as EVD -- known as zoonoses -- are to be tackled effectively, the response must go beyond media focus and immediate medical action when an epidemic hits. There is a crucial need for multidisciplinary working over the longer term to gain a holistic understanding of the causes of these diseases.

This so-called One Health approach takes as its premise an understanding that human health, animal health and environmental health are all interlinked. It calls for collaborative efforts between natural and social scientists -- including doctors, veterinarians, environmental scientists, geographers and anthropologists -- at local, national and international levels.

Such a holistic understanding of health is not new. It is, however, increasingly gaining traction among those in the field, with the veterinary sector proving to be particularly quick to recognise the benefits of One Health. A recent joint research initiative from the Department for International Development (DfID) and the social science, natural environment, medical and bioscience research councils, recognises the benefits of the approach. It aims to fund multidisciplinary research that would, among other benefits, reduce the impact of zoonoses on vulnerable people and their livestock.

When natural and social scientists work together -- not just alongside each other, but meaningfully integrate their findings -- it can be very productive. However, breaking down the barriers between researchers is one thing. The real challenge is to persuade those with the funds and the power to make cross-sector action happen. One of the issues that urgently needs to be tackled is a reconsideration of funding models to help facilitate cross-sector working.

Over the past 40 years, more than 60 percent of emerging infectious diseases affecting people have had their origin in wildlife or livestock. Many of these zoonoses may cause death more slowly than Ebola, and remain unnoticed by anybody outside the immediate populations affected by them, but their effects are often devastating.

Trypanosomiasis is fatal when left untreated, and even when it is, it has a prolonged recovery period. As a result, it can ruin lives and livelihoods. The UN Food and Agricultural Organisation says the disease probably threatens rural development and poverty alleviation in sub-Saharan Africa more than any other disease.

Like EVD, a multidisciplinary approach to understanding trypanosomiasis is essential if it is to be controlled. Take Zambia, where trypanosomiasis has historically acted as a limitation on human settlement, with families keeping away from fertile but highly tsetse-infested areas. Land pressure is increasingly leading to colonisation of these areas. Land clearance for cash crops such as cotton is also thought to be having an effect on tsetse populations, and thus the spread of the disease.

In addition, there are likely to be social differences in vulnerability to trypanosomiasis, based on gender roles, livelihood patterns and the different ways in which people interact with their environment. These points are aside from other, 'macro' changes, such as climate change and urbanisation, which may be having an effect on tsetse ecology and disease transmission. Thus, it can easily be seen how medical research on its own is insufficient to understand and tackle the disease.

The stories behind a host of other zoonoses -- from Rift Valley fever to Ebola virus disease -- are just as complex. Only multidisciplinary research can help to reveal and unravel their complexity. Without a holistic understanding of all the inter-related factors affecting the emergence, transmission and spread of zoonoses, disease management or elimination will remain beyond our reach.

[Byline: Naomi Marks (who works for the Dynamic Drivers of Disease in Africa Consortium)]

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[This call for a One Health approach in tackling EVD is very timely, and reflected by WHO, which sent anthropologists earlier this month (June 2014) into the field to help with public communication.

To put EVD case numbers in perspective, malaria is the number one public health problem in Guinea. According to national health statistics, the morbidity rate for malaria is 148/1000 population (http://www.pmi.gov/docs/default-source/ ... f?sfvrsn=8) or 74 000 cases per year resulting in over 1000 deaths (based on an estimated number of deaths of 8.5/100 000 population (estimated population of Guinea in 2013 = 11 million) (http://www.who.int/malaria/publications ... gin_en.pdf).

There is an up-to-date map of the geographical spread of EVD in West Africa at http://www.aljazeera.com/news/africa/20 ... 24796.html. - Mod.JW

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/54.]
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Ebola-Fieber in Westafrika

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EBOLA VIRUS DISEASE - WEST AFRICA (69): GUINEA, SIERRA LEONE, REGION
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A ProMED-mail post
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ProMED-mail is a program of the
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In this update:
[1] Guinea
[2] Sierra Leone
[3] Sierra Leone: problems
[4] Sierra Leone: Tulane report
[5] Region


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[1] Guinea
Date: Fri 20 Jun 2014
Source: Rappler.com, Agence France-Presse (AFP) report [edited]
http://www.rappler.com/world/regions/af ... us-spreads


Cases have recently surfaced in Guinea's west and southeast -- areas previously thought to be free of the Ebola virus disease (EVD). A 2nd spike in cases has panicked residents and health officials in Guinea, who fear the West African outbreak of the killer disease may now be out of control.

"EVD cases are worrying. We do not know what to expect," Mamady Traore, a trader in the suburbs of the capital Conakry, told AFP on Thursday, 19 Jun 2014. "Sometimes you are told it has been (contained) and sometimes you hear it has reappeared in other towns and villages."

According to figures released by the World Health Organization (WHO) on Wednesday, 18 Jun 2014, a total of 398 cases of hemorrhagic fever -- causing 264 deaths -- have been reported in Guinea since the start of 2014. Of these, 254 were caused by EVD.

The incurable disease [incorrect -- there are now many survivors - Mod.JW] is spread by contact with bodily fluids including sweat, meaning just touching an infected person is enough to spread the virus. "The government can't do anything to fight the disease," taxi driver Abdoulaye Barry said of the ebolavirus, one of the deadliest known viruses, which kills its victims by inducing unstoppable internal bleeding. The latest outbreak began in southeast Guinea and spread rapidly through neighboring Liberia and Sierra Leone. Cases have recently surfaced in Guinea's west and southeast -- areas previously thought to be free of the disease. "We're faced with a 2nd spike in the epidemic," Marie-Christine Ferir, a worker for aid agency Doctors Without Borders, told AFP. "What is unusual is the [wide] spreading of outbreak locations. It complicates things."

On Thursday [19 Jun 2014] in Conakry, there was no discernable presence of medical staff around key buildings. An AFP correspondent said, however, that sanitizing hand gels were offered to customers at the entrances of banks and insurance companies.

A total of 528 hemorrhagic fever cases have been reported throughout West Africa in 2014, inflicting 337 deaths. Almost 70 percent were caused by EVD, which can induce severe fever and muscle pain, as well as vomiting, diarrhea and organ failure.

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[2] Sierra Leone
Date: Fri 20 Jun 2014
Source: Yahoo! News UK & Ireland, Agence France-Presse (AFP) report [edited]
https://uk.news.yahoo.com/sierra-leone- ... 41424.html


Sierra Leone has stepped up measures to fight the highly contagious and deadly Ebola virus disease (EVD), the health minister has said. Miatta Kargbo said Thursday [19 Jun 2014] that the number of registered cases of haemorrhagic fever had risen to 246. Of these, 103 were confirmed to be EVD and 26 had died.

Kargbo told journalists that her figures showed that health workers "have access to places they had difficulty to access" in the past, including the remote Koindu and Kissi Teng chiefdoms in the eastern region. Checkpoints to screen potential Ebola cases were now in place and "functional", the minister added, declaring that the local population had proven increasingly cooperative about taking tests.

Like other haemorrhagic fevers, Ebola causes high fever, vomiting, muscle pain and diarrhoea and can lead to organ failure and unstoppable internal bleeding. It is spread by bodily fluids including sweat, which means that just touching an infected person can spread the virus. There is no [specific] cure and the current strain of Ebola has a [high] death rate, according to medical teams, but patients can be isolated and at least treated for symptoms [and a number do recover - Mod.JW].

Sierra Leonean authorities have also set up a further 13 checkpoints in the eastern towns of Kailahun, Kono and Kenema; 4 health workers stand at each checkpoint with equipment including safety gloves, chlorine, disposable thermometers and mobile phones. In some districts, local personnel are backed up by staff of the medical charity Doctors Without Borders, known by its French acronym MSF, which is also helping out in Guinea and Liberia [possibly not Liberia -- see [5] below - Mod.JW]. WHO is providing Sierra Leone with technical support in fighting the epidemic and recently trained ambulance drivers and medics in safely handling the sick and dead bodies.

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[3] Sierra Leone: problems
Date: Thu 19 Jun 2014
Source: The Economist [edited]
http://www.economist.com/blogs/baobab/2 ... erra-leone


Many people in Sierra Leone, where an ebolavirus epidemic has gripped the country for the 1st time, refuse to accept that the disease can be tackled by Western medicine. They prefer to use traditional healers instead. This may make it spread faster. At least 22 people have died so far; another 96 have been infected there.

The Sierra Leonean authorities are therefore up against both a health-care problem and a cultural one. Traditional healers and herbalists are popular across West Africa. With secret recipes of herbs and potions, they claim to cure everything from the common cold to malaria. We're only looking at the ears of the hippo," says Amara Jambai, Sierra Leone's director of disease prevention and control. "Many cases stay in the communities because people still like to use alternative sources of treatment. So we miss a lot of cases and only capture a few."

Plenty reckon that those who succumb to the disease are victims of a curse fired by a "witch gun"; Western medicine is thought to offer little defence against it. Only a witch doctor can have the curse removed -- for a fee. Official health workers sometimes face physical resistance from those they seek to help. Some have been denied access to the sick; others have been refused blood samples. In one incident, medical staff were stoned by villagers bent on removing ebolavirus patients from a health centre.

Given a health-care system lacking decent equipment, qualified staff and affordable drugs (rather than the more popular counterfeit ones), a lack of faith in Western medicine is understandable. The ministry of health has put out flyers with answers to questions such as "Is it true Ebola is a curse?" and "Can a mix of ginger, honey, garlic, onion and vinegar cure Ebola?" At the same time, the authorities have used mobile-phone networks to warn people by text to avoid eating the meat of [fruit] bats, one of the disease's prime carriers [and a popular food item - Mod.JW]. A band based in neighbouring Liberia, which also has the scourge, has released a catchy new song with lyrics such as "Ebola, Ebola in town/Don't touch your friend/No eating something/It's dangerous".

[Byline: T.T.]

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[4] Sierra Leone: Tulane report
Date: Fri 20 Jun 2014
Source: Awareness Times, Freetown, Sierra Leone [edited]
http://news.sl/drwebsite/publish/articl ... 5613.shtml


Comments and Opinions:
Ebola Update from American Expert
---------------------------------
The Ministry of Health and Sanitation has been giving us what they say are credible statistics. However, Tulane University's Ebola expert [Dr Robert Garry], sent to Sierra Leone from the United States Government, has returned to America, and just a day or so ago on 18 Jun 2014, he gave an interview there which was broadcast all over America's National Public Radio (NPR). His voice is still available for download from the NPR website [

It is recalled that on 18 Jun 2014, health ministry statistics said Sierra Leone only had 22 EVD deaths nationwide so far. Well, on that same date, here is what the EVD expert told Americans by radio:

"There are many villages in the eastern part of Sierra Leone that are basically devastated," virologist Robert Garry of Tulane University tells NPR's Jason Beaubien. "We walked into one village and we found 25 corpses. One house with 7 people, all in one family, were dead. It's a very serious situation there." Garry had just returned to the USA from West Africa. "This is about as bad as an Ebola outbreak gets."

So, the Health Ministry says there are only 22 deaths nationwide, whilst America's expert says in one village alone, they saw 25 dead bodies. So, who is [right]?

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[Dr Garry informs ProMED that the Ministry is probably referring only to deaths in the EVD ward. - Mod.JW]

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[5] Region
Date: Fri 20 Jun 2014
Source: Associated Press (AP) [edited]
http://bigstory.ap.org/article/ebola-ou ... ut-borders


[In the file photo (click on source URL above) taken on Tuesday, 17 Jun 2014, people welcome Liberian President Ellen Johnson Sirleaf outside a hospital as she visits the area after Ebola deaths in Monrovia, Liberia (AP Photo/Jonathan Paye-Layleh). They hold posters reading, "With your visit, Mama Ellen, Ebola will go away", showing a basic lack of understanding of how the disease is transmitted and contained." - Mod.JW]

[Excerpts]
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International organizations and the governments involved need to send in more health experts and to increase the public education messages about how to stop the spread of the disease, Bart Janssens, the director of operations for Doctors Without Borders [MSF] in Brussels told the Associated Press on Friday [20 Jun 2014]. The situation requires a more effective response, and with more than 40 international staff currently on the ground and 4 treatment centers, Doctors Without Borders has reached its limit to respond, he said. "It's the 1st time in an Ebola epidemic where (Doctors Without Borders) teams cannot cover all the needs, at least for treatment centers," he said.

It is unclear, for instance, if the group will be able to set up a treatment center in Liberia, like the ones it is running in in Guinea and Sierra Leone, he said. For one thing, Janssens said, the group doesn't have any more experienced people in its network to call on. As it is, some of its people have already done 3 tours on the ground.

Janssens said this outbreak is particularly challenging because it began in an area where people are very mobile and has spread to even more densely populated areas, like the capitals of Guinea and Liberia. The disease typically strikes sparsely populated areas in central or eastern Africa, where it spreads less easily, he said. By contrast, the epicenter of this outbreak is near a major regional transport hub, the Guinean city of Gueckedou.

He said the only way to stop the disease's spread is to persuade people to come forward when symptoms occur and to avoid touching the sick and dead. "There is still not a real change of behavior of the people," he said. "So a lot of sick people still remain in hiding or continue to travel. And there is still news that burial practices are remaining dangerous."

[Byline: Sarah DiLorenzo; Bishr Eltouni and Jonathan Paye-Layleh contributed to this report]

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[I'm not convinced that more white-skinned experts can help with public communication in this area of Africa, where the common belief is that the outsiders bring the disease. After all, it is always worse in the places where they are working (the local people do not understand that of course the experts go to the areas where there are the most cases, to bring urgent aid). As a blogger has pointed out, if a bunch of outsiders with a different skin colour came to our community and told us our traditional beliefs in the causes of disease, the burial practices we have followed for generations, and one of our favourite foods were responsible for making the epidemic worse, we would take a lot of convincing. Even in developed countries, there are movements against vaccinations, which have saved many more lives than herbal remedies.

Looking at the map, it is remarkable that we don't have confirmed reports of EVD from across the borders of the affected region, in the contiguous forested areas of Senegal, Gambia, Mali, Guinea-Bissau or Cote d'Ivoire. (The forest belt can be clearly seen on Google Earth by searching for West Africa). But there is no surplus manpower or funds for outsiders to go looking there, and those African governments probably don't want to know if they have the ebolavirus for fear of the implications. However, Senegal and Gambia do have contingency plans in place -- see ProMED-mails archives (35) and (62) at the end of this post -- and there has been a call for action in Nigeria (ProMED-mail archive (49) below).

There is an up-to-date map of EVD's geographical spread at http://www.aljazeera.com/news/africa/20 ... 24796.html. - Mod.JW

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/46.]
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Ebola-Fieber in Westafrika

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EBOLA VIRUS DISEASE - WEST AFRICA (70): SIERRA LEONE, LIBERIA, TRAVEL ADVICE
****************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this update:
[1] Region
[2] Sierra Leone: hospital closure
[3] Liberia: one more death
[4] Liberia: child case negative
[5] Travel advice


******
[1] Region
Date: Sat 21 Jun 2014
Source: Rappler.com, Agence France-Presse (AFP) report [edited]
http://www.rappler.com/world/regions/eu ... on-efforts


The recent rapid spread of Ebola in 3 countries in West Africa has come in part because efforts to contain the deadly virus have been relaxed, Pierre Formenty, a World Health Organization specialist, told Agence France-Presse (AFP) on Saturday, [21 Jun 2014].

Question: We have around 530 cases of hemorrhagic fever, mostly from the Ebola virus, in the region, compared to 225 at the end of April [2014]. How do you explain this leap?

Answer: We have had since [21 Mar 2014], when the epidemic was declared in Guinea, a 1st wave that has started to diminish. Since the start of May [2014] we have had a sort of resurgence with an increase in the number of cases and notably also with an epidemic which has spread to Sierra Leone and Liberia. We are seeing a 2nd wave of cases for West Africa.

Q: How do you explain this new peak?

A: When the epidemic started, it was a little under-estimated, so that the states took a while to really prepare themselves. At the end of April [2014], we started to see a decrease in the number of cases and we maybe saw a relaxation by the teams in the 3 countries, and this relaxation allowed things to restart. In addition, there were some problems with the affected populations which were sometimes not fully listened to.

Q: Were the right measures implemented?

A: The most important things are monitoring and communication. States are getting better and better, but the problems of communication continue. The medical corps on their own cannot stop this epidemic. It is only with the help of the population that we can fight this epidemic and stop it.

Q: What are the specific features of this epidemic?

A: The epidemic is pretty much identical in the 3 countries. What's really important in this epidemic is that the majority of cases are cases of human-to-human transmission, by contact, especially during care, but also during funerals because it is particularly when victims are deceased that Ebola is present around the body.

Q: How did the epidemic spread?

A: The epicentre of this epidemic is in the forested border zone around the town of Gueckedou (in the south of Guinea), and now it has spread to the district of Kailahun in Sierra Leone and the district of Lofa in Liberia. It has been spread most of all by people who travel to Conakry or Monrovia for healthcare. These people travel a great deal. As soon as they are sick with the symptoms, even if they know that it might be Ebola, they will go see friends in one town or another and that's how the disease spreads.

Q: Why is it important for the authorities and humanitarian agencies to communicate with the populations?

A: One case can restart an entire epidemic. So these dramatic measures, which are not put in place for other diseases like meningitis or measles, are hard for the populations to understand. In an area where the quality of health services are not optimal, the populations have struggled to understand why we were asking them to make such an effort and probably we have not been able to explain both the disease and the means of control to the populations.

Q: What is the latest assessment of the WHO?

A: As of 17 Jun 2014, we had 528 cases of Ebola, including confirmed, probable and suspected cases. Included in these 528 cases are 337 dead. All the deaths are confirmed, probable or suspected cases of Ebola. At the level of the international community, Doctors Without Borders [MSF], WHO and other international partners have mobilised 100 to 160 international experts who are on the ground and who are working hard. In Conakry, for patients admitted (to hospital) we have been able to reduce the mortality rate to 40 percent.

[Let's say, rather, that this epidemic was expected to be controlled quickly, just as previous outbreaks in Africa have always been. But because of the hiding of cases, funeral practices and extensive cross-border travel, this time it has been different. However, the mortality rate in Conakry is less than half the frequently quoted 90 percent. - Mod.JW]

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[2] Sierra Leone: hospital closure
Date: Fri 20 Jun 2014
Source: All Africa, The News (Monrovia) report [edited]
http://allafrica.com/stories/201406200896.html


Investigation conducted by this paper has revealed that workers at the Redemption Hospital in New Kru Town have abandoned the hospital for fear of more deaths from the deadly Ebola virus. The decision of workers to stay away from work has led to the closure of the Hospital.

Authorities at the Ministry of Health told journalists at the Ministry of Information regular press briefing that the hospital was temporarily shut down after nurses decided to stay away, but has since been reopened and was carrying on normal medical operations.

Assistant Health Minister for Preventive Services, Tolbert Nyenswah, blamed the brief closure of the hospital on the trauma suffered by nurses and other health workers following the death of their colleague, E.K.

Nyenswah said the situation is under control. He said nurses and workers are going about their normal duties at the hospital.

But contrary to the Minister's assertion, our investigation established that nurses and other health workers at the hospital have decided to stay away from the hospital until the government and the hospital's administration ensure that the entire hospital's environment is sprayed and they (nurses) are supplied the necessary protective gears before returning to work.

A nurse who chose anonymity (for fear of losing her job) said since the death of their colleague, E.K., of the deadly Ebola virus, they unconditionally discharged all of the patients that were admitted at the hospital and have refused to accept new patients.

She said their non-corporative action will continue until the government provides them with the needed materials to work with, especially during the 'Ebola crisis' period.

Nurses at the Redemption Hospital told reporters Tuesday [17 Jun 2014] that their lives were at risk in the performance of their daily duties after the death of their colleague. The nurses said they work in a risky environment especially in the wake of the reported outbreak of the deadly Ebola virus in the New Kru Town community. The assertions and stay-away action of the Redemption nurses and other workers also contradict comments by the Hospital's Interim General Administrator who claimed that the nurses were provided with the necessary protective gear to carry on their work.

[Byline: Sam Zota, Jr.]

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[3] Liberia: one more death
Date: Fri 20 Jun 2014
Source: Vice News [edited]
https://news.vice.com/article/eight-now ... as-capital


The spread of the Ebola virus into the Liberian capital of Monrovia has claimed another life, according to a statement from the country's Ministry of Health and Social Welfare (MOHSW) today [20 Jun 2014]. The news comes as public health officials ramp up efforts and struggle to maintain enough manpower to combat the outbreak that began in Guinea this spring [2014].

Earlier this week, Liberia's health minister said 7 people had died from Ebola in Monrovia since [8 Jun 2014]. Friday's [20 Jun 2014] MOHSW statement confirmed an 8th death. Today's news brings Liberia's total lab confirmed death count up to 17, with at least another 7 suspected. The country had gone nearly 2 months without any new reported cases.

[Byline: Kayla Ruble]

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[4] Liberia: child case negative
Date: Fri 20 Jun 2014
Source: All Africa, The New Dawn (Monrovia) report [edited]
http://allafrica.com/stories/201406200126.html


President Ellen Johnson-Sirleaf has called on Liberians to see the deadly Ebola virus disease (EVD) in the country as a national emergency and stop politicizing the issue, stressing that a united front will complement the efforts of government and its partners to successfully fight the virus.

According to the Executive Mansion, President Sirleaf paid a visit to the Redemption Hospital in the Borough of New Kru Town on Tuesday, 17 Jun 2014, to show solidarity for staff and nurses there after the death of a staff member, who contacted the ebolavirus.

In the wake of a renewed outbreak of the virus in Liberia, the President has expressed government's commitment to fighting the pandemic. During the visit to the hospital, the President sympathized with the administration, nurses and staff, who are mourning the loss of a colleague, E.K. The Liberian leader also ascertained the state of affairs of the Redemption Hospital relative to its preparedness to cope with an influx of patients if the need arises. She paid tribute to the administration, nurses and staff for their courage and sacrifices to the nation and promised government's fullest support. [But there seems to have been a breakdown in the provision of PPE (personal protective equipment) to hospital staff -- see [1] above. - Mod.JW]

The Ministry of Health and Social Welfare recently announced a renewed outbreak of EVD in the New Kru Town vicinity that has claimed the lives of at least 7 persons, including a health worker at the Redemption Hospital, who was infected by the virus while attending to a patient.

Speaking earlier, the Assistant Minister of Health for Curative Services, Tolbert Nyenswah, informed President Sirleaf of the challenges faced by health workers in the fight against the outbreak, including fear and denial. He explained that nurses at the Redemption Hospital are seriously shocked by the death of their colleague, which has also affected their passion to work in the wake of fear of being infected by the virus while attending to suspected cases. Mr. Nyenswah disclosed that based on the demand of health workers since the death of their colleague, the administration has fumigated all the strategic areas at the hospital which has helped to alleviate their fear.

He however highlighted that family members of Ebola victims are posing a serious hindrance to the instant burial of these fatalities which is one of the surest ways of prevention. Minister Nyenswah said family members were demanding the remains of dead relatives for burial in keeping with normal traditions -- he warned that if not curtailed, the practice could hinder prevention efforts.

The World Health Organization Representative to Liberia, Dr. Nestor Ndayimirije, who provided updates to President Sirleaf on the recent outbreak, agreed with Assistant Minister Nyenswah that government and its partners were not only fighting the ebolavirus but also trying to allay the fear that has caused health workers to sometimes desert patients. He indicated that the Liberian leader's visit to the hospital was a great motivation to the health workers in dealing with the fear.

Child with suspected EVD tested negative
----------------------------------------
Meanwhile, authorities at the James N. Davies Memorial Hospital in Nezoe Community, Paynesville [Montserrado county], have clarified that the death of 11-year-old T.J., at the hospital recently was not related to the ebolavirus. Little T.J. was a resident of Rehab Community. He was taken to the James N. Davies Memorial Hospital with blood oozing from his body, but was pronounced dead 2 days later. A laboratory technician at the hospital David Mulbah, told The New Dawn that the remains of the deceased was held for 2 days for necessary tests to establish whether the death was EVD related, but they proved negative. Mulbah said blood oozing from the body is one symptom of the Ebola virus, but all tests performed on the victim showed that he was negative. The laboratory technician however, did not disclose what killed little T.J. He said family of the deceased has been granted permission to pick up the body for burial. "If he had died from EVD then the Government would have kept the body for the safety of the family", he added.

[Byline: Ethel A. Tweh]

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[The 1st child fatality of the epidemic was reported in ProMED archive (68) -- see below. It is paradoxical that all confirmed cases so far have been in adults. Certainly infants and toddlers, if not older children, would be in close enough contact with their mothers to be at risk of contagion. - Mod.JW]

******
[5] Travel advice
Date: Wed 28 May 2014
Source: Public Health Agency of Canada [edited]
http://www.phac-aspc.gc.ca/tmp-pmv/noti ... php?id=125


[Although WHO does not recommend any travel or trade restrictions be applied to Guinea, Liberia, or Sierra Leone based on the current information available for this event, people who unavoidably have to travel to those countries might appreciate the advice from Public Health Canada below. - ProMED]

Ebola Outbreak in West Africa: Travel Health Notice Updated: 28 May 2014
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The Ministry of Health of Guinea continues to report on the evolving outbreak of Ebola virus disease (EVD, formerly known as Ebola haemorrhagic fever). Confirmed cases have been reported in several districts in Guinea. Confirmed cases in the neighbouring countries of Liberia and Sierra Leone have also been reported and additional cases can be expected.

The Ministries of Health of Guinea, Liberia and Sierra Leone are working with the World Health Organization (WHO) and other partners to implement measures to control the outbreak and prevent further spread. The WHO does not recommend that any travel or trade restrictions be applied to Guinea, Liberia or Sierra Leone in relation to this outbreak.

For the latest updates on Ebola virus disease, including the total number of cases and deaths, please visit the World Health Organization's Global Alert and Response website (http://www.who.int/csr/don/en).

Ebola virus disease is a rare and severe viral disease. The virus can infect both humans and non-human primates (monkeys, gorillas, etc.). When infected, people can get very sick, with fever, intense weakness, headache, sore throat and pains, and may bleed from different parts of the body (i.e., haemorrhage).

The risk of infection is low for most travellers, although the risk may increase for those who are working in a health care setting since most human infections result from direct contact with the bodily fluids of infected patients. The Public Health Agency of Canada recommends travellers avoid all direct contact with a person or corpse infected with the Ebola virus. Also, avoid contact with or handling an animal suspected of having Ebola. Travellers should immediately seek medical attention at the 1st sign of illness.

Recommendations
---------------
- Consult a health care provider or visit a travel health clinic at least 6 weeks before you travel.
- Avoid direct contact with blood and other bodily fluids of people with Ebola virus disease or unknown illnesses.
- Avoid direct contact with bodies of people who died of Ebola virus disease or unknown illnesses.
- Avoid unprotected sexual intercourse with an infected person or a person recovering from Ebola virus disease.
- Avoid contact with any objects, such as needles, that have been contaminated with blood or bodily fluids.
- Health care workers should practise strict infection control measures including the use of personal protective equipment (i.e., gowns, masks, goggles and gloves).
- Avoid close contact with or handling of wild animals.
- Avoid live or dead animals, as both can spread the virus. Animals such as chimpanzees, gorillas, monkeys, forest antelope, pigs, porcupines, duikers and fruit bats may be carriers.
- Avoid handling of raw or undercooked wild meat.
- Know the symptoms of Ebola virus disease and see a health care provider if they develop during travel or within 3 weeks after your return.
- If you have symptoms upon arrival into Canada, tell a flight attendant or a border services officer when you arrive. They will determine whether you need further medical assessment.
- Seek medical attention immediately, if a fever and any other symptoms arise during or after travel.
- Be sure to tell your healthcare provider that you have travelled to a region where Ebola virus disease was present.

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Ebola-Fieber in Westafrika

Beitrag von Birgitt »

EBOLA VIRUS DISEASE - WEST AFRICA (71): GUINEA, SIERRA LEONE, NIGERIA, SEROLOGY
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In this update:
[1] Guinea
[2] Sierra Leone: Ebolavirus in 2008
[3] Nigeria: Ebolavirus in 1987


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[1] Guinea
Date: 21 Jun 2014
Source: Interaksyon, Philippines [edited]
http://www.interaksyon.com/article/8961 ... -in-guinea


Four new cases of Ebola virus disease (EVD) have been reported in Guinea, bringing the total number to 258 [lab confirmed] in the west African nation, the country's health authorities said on Friday [20 Jun 2014]. There were 3 new cases in Guekedou and one in Boffa. At the same time, 2 people died from the disease in Telemele, and one died in the Boffa region.

Due to the continued spread of the disease, health authorities have launched sensitization campaigns to urge the population to wash their hands as a way of preventing contamination by ebolavirus.

Statistics showed that since January [2014], there have been 258 EVD [confirmed] cases reported across the country, of which 160 have died. The southern region that borders Liberia and Sierra Leone has been the epicenter of the epidemic, with 139 cases and 102 deaths.

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[2] Sierra Leone: Ebolavirus in 2008
Date: 12 Jun 2014
Source: Emerging Infectious Disease [edited]
http://dx.doi.org/10.3201/eid2007.131265


Schoepp RJ, Rossi CA, Khan SH, Goba A, Fair JN. Undiagnosed acute viral febrile illnesses, Sierra Leone. Emerg Infect Dis [Internet]. 2014 Jul [12/06/2014] http://dx.doi.org/10.3201/eid2007.131265.

Abstract
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Sierra Leone in West Africa is in a Lassa fever-hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of 500-700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in eastern Sierra Leone. Generally, only 30-40 percent of samples tested are positive for Lassa virus (LASV) antigen and/or LASV-specific IgM; thus, 60-70 percent of these patients have acute diseases of unknown origin. To investigate what other arthropod-borne and hemorrhagic fever viral diseases might cause serious illness in this region and mimic Lassa fever, we tested patient serum samples that were negative for malaria parasites and LASV. Using IgM-capture ELISAs, we evaluated samples for antibodies to arthropod-borne and other hemorrhagic fever viruses. Approximately 25 percent of LASV-negative patients had IgM to dengue, West Nile, yellow fever, Rift Valley fever, chikungunya, ***Ebola [EBOV, Ebola-Zaire], and ***Marburg [MBGV] viruses but not to Crimean-Congo hemorrhagic fever virus [my asterisks - Mod.JW].

Results
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We tested serum samples from 253 patients submitted to the Lassa Diagnostic Laboratory during 2006-2008 for IgM to the arthropod-borne and hemorrhagic fever viruses of interest (Table 2 in source) ... Antibody prevalence to the hemorrhagic fever viruses, EBOV and MBGV, were 8.6 percent and 3.6 percent, respectively. ...

Because the samples submitted to the Lassa Diagnostic Laboratory were from patients with acute illness, IgM-capture ELISAs were used to detect the earliest antibody elicited in response to viral infection. We found evidence of IgM for ... the filoviruses EBOV and MBGV (Table 2 in source). ...

PRNT [plaque reduction neutralization test] is the laboratory standard for immunologic assays. It measures in vitro virus neutralization and is the most virus-specific serologic test to confirm immunologic test results. ... PRNT results for the ebolaviruses clearly indicated that most resulted from EBOV infections (Table 4 in source). We found evidence that SUDV [Ebola-Sudan] was responsible for one infection but no evidence for TAFV [Ebola-Tai Forest (Cote d'Ivoire)] infection, the only ebolavirus isolated in West Africa. In the ebolavirus PRNTs, we did not include the newest discovered ebolavirus, Bundibugyo virus [from Uganda], which cross-reacts with EBOV in immunoassays. Ebolavirus infections in Sierra Leone might be the result of Bundibugyo virus or an ebolavirus genetic variant and not EBOV.

Discussion
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The filoviruses represented the largest group of patient samples that reacted in our study. This finding was surprising because no filovirus has been reported in the region or in West Africa other than the initial isolation of TAFV in Cote d'Ivoire. These serologic results provide evidence that ebolaviruses are circulating and infecting humans in West Africa. All of the ebolavirus-reactive samples demonstrated only IgM and no evidence of IgG, suggesting acute infection. PRNT results indicated that the infecting virus was most closely related to EBOV, except for one SUDV-reactive patient sample. This finding was unexpected because our assumption was that any ebolavirus would more likely be TAFV, the only species described in West Africa. Although the serum samples were able to neutralize EBOV only at a low level (1:40 dilution), it is possible that the virus is an EBOV genetic variant. This presumptive diagnosis of EBOV infection extends the ebolavirus geographic region to Sierra Leone and the surrounding region.

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[Prophetic. - Mod.JW]

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[3] Nigeria: Ebolavirus in 1987
Date: 14 Jun 2014
Source: Am J Trop Med Hyg [edited]
[PubMed - indexed for MEDLINE, requires password access]


Tomori O1, Fabiyi A, Sorungbe A, Smith A, McCormick JB. Viral hemorrhagic fever antibodies in Nigerian populations. Am J Trop Med Hyg. 1988 Mar;38(2):407-10. PMID: 3128130.


Abstract
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Using the immunofluorescence test, a serosurvey for antibodies to 5 viral agents associated with hemorrhagic febrile infections was conducted with 1677 human sera from different parts of Nigeria.

Antibodies to Ebola and Marburg viruses were detected in 30 and 29 sera, respectively. ... Sera positive for Marburg were positive in combination with Lassa, Ebola, or Rift Valley fever viruses. Antibodies to Lassa and Rift Valley fever viruses were found in all locations in Nigeria, whereas Ebola and Marburg antibodies were found mainly in the northern savanna zones of Benue and Gongola, but not in the rain forest area of Ondo.

On testing 30 EBO virus (Sudan) strain-positive sera against the EBO virus (Zaire) strain, only 22 were found to have antibody titers greater than or equal to 10 [commonly accepted at the time as positive - Mod.JW]. In general, antibody titers against EBO virus (Sudan) were higher than against EBO virus (Zaire).

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[The date of collection of the sera is not given in the full text, but given the publication date of 1988, it seems reasonable to deduce that they were collected in an earlier year. There are 2 notable observations in the paper: The reservoir of ebolavirus is thought to be a forest mammal, yet human seropositives were found mainly in the savanna; and the stronger reactions were to the Sudan ebolavirus, yet the current West African strain has been typed as closest to the Zaire strain.

There seems to have been serological evidence of ebolaviruses in West Africa in years past, detected by researchers in Nigeria and the USA. - Mod.JW

HealthMap/ProMED-mail maps can be accessed at: http://healthmap.org/promed/p/45, http://healthmap.org/promed/p/46, http://healthmap.org/promed/p/62.]
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