MARBURG VIRUS DISEASE - UGANDA (06): (KABALE, IBANDA) NEW CASES
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Date: Sun 28 Oct 2012
Source: Daily Monitor [edited]
http://www.monitor.co.ug/News/National/ ... index.html
New Marburg case reported in Ibanda
----------------------------------
The deadly Marburg virus has claimed 2 more lives, raising the death toll to 7 and scaling up the infected areas.
The 50-year-old mother of the former [deceased] Kabale Regional Referral Hospital mortuary attendant, succumbed to the disease in less than 6 hours after she tested positive. Another person was confirmed dead in Ibanda District, medical officials said. The Kabale District Health Officer, Dr Patrick Tusiime, told this newspaper yesterday [27 Oct 2012] that a retired resident of Bukora Village, Kitumba Sub-county [Kabale district], died in the isolation unit at Rushoroza Health Centre III shortly after midnight.
"A total of cumulative Marburg virus [disease] cases both probable and confirmed in Kabale District is now 14. The total number of admissions at the isolation unit is 7 and the total number of people that got into close contact with the Marburg virus disease victims is now 198. The situation is becoming complicated," Dr Tusiime said.
Marburg virus disease experts currently in Kabale have released a report indicating that a new Marburg case has been confirmed in Ibanda. "The new Marburg virus disease in Ibanda case is of a 32-year-old woman, resident of Sigiria Village, Kihani Parish in Kinkye Sub-county. She was admitted at Mbarara Regional Referral Hospital on 19 Oct 2012 and died 5 days later after having miscarriage. The specimens were collected from her body and they tested Marburg virus positive and a supervised burial was conducted. 7 people that [had] close contact with the deceased have been listed and are being followed up," according to a report issued by Dr Tusiime and the Marburg epidemic experts.
[This report also describes] another of the Marburg victims who was discharged after specimens collected from him tested negative, 6 days after he was admitted at the isolation unit. "[This patient] had lost his 2 brothers, a sister and a mother to Marburg virus disease. The specimens from him tested Marburg positive after he had escaped to Rukungiri for spiritual healing. The Marburg virus experts in Kabale traced him and he was admitted to the isolation unit. Specimens were taken from him again and on 26 Oct 2012 tested negative and he was discharged," Dr Tusiime said.
[Byline: Robert Muhereza]
--
Communicated by:
ProMED-mail Rapporteur Mary Marshall
[The death toll in the Marburg virus disease outbreak in Kabale has now risen from 5 to 7, and the total number of confirmed cases is now 14. A total of 198 people are under surveillance, an increase of 2 since the previous report on 26 Oct 2012. Most, if not all, of the deceased patients appear to be members of the same family. The infection is highly lethal, but does not appear to be spreading rapidly. The conflicting results of diagnostic testing in one case is troubling.
The District of Kabale is located approximately 420 km (261 mi) southwest of Kampala, the capital city of Uganda. A map of the districts of Uganda can be accessed at http://en.wikipedia.org/wiki/Districts_of_Uganda. The HealthMap/ProMED-mail interactive map can be accessed at http://healthmap.org/r/3NfD. - Mod.CP]
Marburg-Fieber in Uganda
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Marburg-Fieber in Uganda | Kabale Distrikt
MARBURG VIRUS DISEASE - UGANDA (07): (KABALE), FURTHER DEVELOPMENTS
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A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
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[1]
Date: Mon 29 Oct 2012
Source: The Daily Monitor [edited]
http://www.monitor.co.ug/News/National/ ... index.html
Testing of specimens from suspected Marburg virus disease victims has begun in Kabale District at the isolation centre set up at Rushoroza Health Centre III. The district health officer, Dr Patrick Tusiime, yesterday [28 Oct 2012] confirmed the development, saying donors from the United States Centres for Disease Control are funding the programme. "A field laboratory for testing samples from suspected victims has started operating. This will save us time and logistics that we have been spending to transport the samples to the Uganda Virus Research Institute in Entebbe," Dr Tusiime said. He said 8 patients are currently admitted at the isolation centre in critical condition, and the total number of people that got in close contact with the Marburg virus disease victims in Kabale district has increased from 198 to 204.
He said 2 more victims that died on Sat 26 Oct 2010 in their homes have been buried under strict supervision of epidemic experts in Muko and Maziba sub-counties. "The relatives of the deceased said they were bleeding from the nose, were vomiting, and had high body temperature," he said.
Student nurses from the Kabale School of Comprehensive Nursing and Kabale Health Institute have been temporarily stopped from going to the wards at Kabale Regional Referral Hospital for nursing practice to reduce congestion of health workers at the ward that might result in spread of the virus.
The Ministry of Health declared an outbreak of the Marburg virus in Kabale last week after 5 people were confirmed to have died of the disease. So far, 7 people have died as a result.
[Byline: RobeertMuhereza]
--
Communicated by:
ProMED-mail Rapporteur Mary Marshall
[Since the previous report posted earlier today (29 Oct 2012), the number of fatalities remains 7, whereas the number of people under surveillance has increased from 198 to 204. The availability of diagnostic testing on site in Kabale is a welcome development that should eliminate some of the ambiguities and ultimately aid the containment of the outbreak. - Mod.CP]
******
[2]
Date: Thu 4 Oct 2012
Source: PLoS Pathog 8(10): e1002877.doi:10.1371/journal.ppat.1002877 [abridged & edited]
http://www.plospathogens.org/article/in ... at.1002877
Seasonal Pulses of Marburg Virus Circulation in Juvenile _Rousettus aegyptiacus_ Bats Coincide with Periods of Increased Risk of Human Infection. [Authors: Amman BR, Carroll SA, Reed ZD, Sealy TK, Balinandi S, et al.]
Abstract:
-----------
Marburg virus (family _Filoviridae_) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases among miners infected in 2007 at the Kitaka mine, Uganda, which contained a large population of Marburg virus-infected _Rousettus aegyptiacus_ fruit bats. Described here is an ecologic investigation of Python Cave, Uganda, where an American and a Dutch tourist acquired Marburg virus infection in December 2007 and July 2008. More than 40 000 _R. aegyptiacus_ were found in the cave and were the sole bat species present.
Between August 2008 and November 2009, 1622 bats were captured and tested for Marburg virus. Q-RT-PCR analysis of bat liver/spleen tissues indicated about 2.5 percent of the bats were actively infected, 7 of which yielded Marburg virus isolates. Moreover, Q-RT-PCR-positive lung, kidney, colon and reproductive tissues were found, consistent with potential for oral, urine, fecal or sexual transmission. The combined data for _R. aegyptiacus_ tested from Python Cave and Kitaka mine indicate low level horizontal transmission throughout the year. However, Q-RT-PCR data show distinct pulses of virus infection in older juvenile bats (about 6 months of age) that temporarily coincide with the peak twice-yearly birthing seasons. Retrospective analysis of historical human infections suspected to have been the result of discrete spillover events directly from nature found 83 percent (54/65) of events occurred during these seasonal pulses in virus circulation, perhaps demonstrating periods of increased risk of human infection. The discovery of 2 tags at Python Cave from bats marked at Kitaka mine, together with the close genetic linkages evident between viruses detected in geographically distant locations, are consistent with _R. aegyptiacus_ bats existing as a large meta-population with associated virus circulation over broad geographic ranges. These findings provide a basis for developing Marburg virus disease risk reduction strategies.
Author Summary:
--------------
Marburg virus, like its close relative Ebola virus, can cause large outbreaks of hemorrhagic fever with case fatalities nearing 90 percent. For decades, the identity of the natural reservoir was unknown. However, in 2007, Marburg viruses were isolated directly from Egyptian fruit bats (_Rousettus aegyptiacus_) that inhabited a Ugandan gold mine where miners were previously infected. Soon after, 2 tourists became infected with Marburg virus after visiting nearby Python Cave, a popular attraction in Queen Elizabeth National Park, Uganda. This cave also contained _R. aegyptiacus_ bats (around 40 000 animals). These events prompted a long-term investigation of Python Cave to determine if, 1) _R. aegyptiacus_ in the cave carried infectious Marburg virus genetically similar to that found in the tourists, and 2) [to determine] what ecological factors might influence virus spillover to humans. In the study, we found that, 1) approximately 2.5 percent of the bat colony is actively infected at any one time and that virus isolates from bats are genetically similar to those from infected tourists, and 2) specific age groups of bats (juveniles around 6 months of age) are particularly likely to be infected at specific times of the year that roughly coincide with historical dates of Marburg virus spillover into humans.
--
Communicated by:
ProMED-mail <promed@promedmail.org>
[Interested readers should read the full account of this research via the source URL>.
The above research further implicates fruit bats as the source of the virus responsible for the sporadic outbreaks of the highly lethal Marburg virus in the human populations of West Africa. The availability of on-site diagnostics is a significant development that should accelerate the containment of Marburg disease outbreaks. - Mod.CP
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/r/1wa6.]
*******************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
[1]
Date: Mon 29 Oct 2012
Source: The Daily Monitor [edited]
http://www.monitor.co.ug/News/National/ ... index.html
Testing of specimens from suspected Marburg virus disease victims has begun in Kabale District at the isolation centre set up at Rushoroza Health Centre III. The district health officer, Dr Patrick Tusiime, yesterday [28 Oct 2012] confirmed the development, saying donors from the United States Centres for Disease Control are funding the programme. "A field laboratory for testing samples from suspected victims has started operating. This will save us time and logistics that we have been spending to transport the samples to the Uganda Virus Research Institute in Entebbe," Dr Tusiime said. He said 8 patients are currently admitted at the isolation centre in critical condition, and the total number of people that got in close contact with the Marburg virus disease victims in Kabale district has increased from 198 to 204.
He said 2 more victims that died on Sat 26 Oct 2010 in their homes have been buried under strict supervision of epidemic experts in Muko and Maziba sub-counties. "The relatives of the deceased said they were bleeding from the nose, were vomiting, and had high body temperature," he said.
Student nurses from the Kabale School of Comprehensive Nursing and Kabale Health Institute have been temporarily stopped from going to the wards at Kabale Regional Referral Hospital for nursing practice to reduce congestion of health workers at the ward that might result in spread of the virus.
The Ministry of Health declared an outbreak of the Marburg virus in Kabale last week after 5 people were confirmed to have died of the disease. So far, 7 people have died as a result.
[Byline: RobeertMuhereza]
--
Communicated by:
ProMED-mail Rapporteur Mary Marshall
[Since the previous report posted earlier today (29 Oct 2012), the number of fatalities remains 7, whereas the number of people under surveillance has increased from 198 to 204. The availability of diagnostic testing on site in Kabale is a welcome development that should eliminate some of the ambiguities and ultimately aid the containment of the outbreak. - Mod.CP]
******
[2]
Date: Thu 4 Oct 2012
Source: PLoS Pathog 8(10): e1002877.doi:10.1371/journal.ppat.1002877 [abridged & edited]
http://www.plospathogens.org/article/in ... at.1002877
Seasonal Pulses of Marburg Virus Circulation in Juvenile _Rousettus aegyptiacus_ Bats Coincide with Periods of Increased Risk of Human Infection. [Authors: Amman BR, Carroll SA, Reed ZD, Sealy TK, Balinandi S, et al.]
Abstract:
-----------
Marburg virus (family _Filoviridae_) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases among miners infected in 2007 at the Kitaka mine, Uganda, which contained a large population of Marburg virus-infected _Rousettus aegyptiacus_ fruit bats. Described here is an ecologic investigation of Python Cave, Uganda, where an American and a Dutch tourist acquired Marburg virus infection in December 2007 and July 2008. More than 40 000 _R. aegyptiacus_ were found in the cave and were the sole bat species present.
Between August 2008 and November 2009, 1622 bats were captured and tested for Marburg virus. Q-RT-PCR analysis of bat liver/spleen tissues indicated about 2.5 percent of the bats were actively infected, 7 of which yielded Marburg virus isolates. Moreover, Q-RT-PCR-positive lung, kidney, colon and reproductive tissues were found, consistent with potential for oral, urine, fecal or sexual transmission. The combined data for _R. aegyptiacus_ tested from Python Cave and Kitaka mine indicate low level horizontal transmission throughout the year. However, Q-RT-PCR data show distinct pulses of virus infection in older juvenile bats (about 6 months of age) that temporarily coincide with the peak twice-yearly birthing seasons. Retrospective analysis of historical human infections suspected to have been the result of discrete spillover events directly from nature found 83 percent (54/65) of events occurred during these seasonal pulses in virus circulation, perhaps demonstrating periods of increased risk of human infection. The discovery of 2 tags at Python Cave from bats marked at Kitaka mine, together with the close genetic linkages evident between viruses detected in geographically distant locations, are consistent with _R. aegyptiacus_ bats existing as a large meta-population with associated virus circulation over broad geographic ranges. These findings provide a basis for developing Marburg virus disease risk reduction strategies.
Author Summary:
--------------
Marburg virus, like its close relative Ebola virus, can cause large outbreaks of hemorrhagic fever with case fatalities nearing 90 percent. For decades, the identity of the natural reservoir was unknown. However, in 2007, Marburg viruses were isolated directly from Egyptian fruit bats (_Rousettus aegyptiacus_) that inhabited a Ugandan gold mine where miners were previously infected. Soon after, 2 tourists became infected with Marburg virus after visiting nearby Python Cave, a popular attraction in Queen Elizabeth National Park, Uganda. This cave also contained _R. aegyptiacus_ bats (around 40 000 animals). These events prompted a long-term investigation of Python Cave to determine if, 1) _R. aegyptiacus_ in the cave carried infectious Marburg virus genetically similar to that found in the tourists, and 2) [to determine] what ecological factors might influence virus spillover to humans. In the study, we found that, 1) approximately 2.5 percent of the bat colony is actively infected at any one time and that virus isolates from bats are genetically similar to those from infected tourists, and 2) specific age groups of bats (juveniles around 6 months of age) are particularly likely to be infected at specific times of the year that roughly coincide with historical dates of Marburg virus spillover into humans.
--
Communicated by:
ProMED-mail <promed@promedmail.org>
[Interested readers should read the full account of this research via the source URL>.
The above research further implicates fruit bats as the source of the virus responsible for the sporadic outbreaks of the highly lethal Marburg virus in the human populations of West Africa. The availability of on-site diagnostics is a significant development that should accelerate the containment of Marburg disease outbreaks. - Mod.CP
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/r/1wa6.]
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Marburg-Fieber in Uganda | Kampala sowie Distrikte Kabale, Ibanda, Mbarara und Kabarole
Marburg haemorrhagic fever in Uganda - update
31.10.2012 - WHO
As of 28 October 2012, a total of 18 cases and 9 deaths, including a health worker, have been reported from 5 districts namely Kabale district, in south-western Uganda, Kampala (the capital city), Ibanda, Mbarara and Kabarole. The case fatality rate is 50%. The outbreak was declared by the Ministry of Health in Uganda on 19 October 2012. Blood samples from 9 cases have been confirmed for Marburg virus at the Uganda Virus Research Institute (UVRI).
Currently, 13 patients have been admitted to hospital (2 in Kampala, 8 in Kabale, 3 in Ibanda) and their contacts are listed for daily follow up. The latest confirmed case was admitted to Ibanda district isolation ward on 26 October 2012.
The World Health Organization (WHO) and international partners including, the Centers for Disease Control and Prevention (CDC), the Uganda Red Cross (URCS), African Field Epidemiology Network (AFENET) and Médecins-Sans-Frontières (MSF) are supporting the national authorities in outbreak investigation and response. The national task force has identified additional health care workers and epidemiologists to strengthen the teams in the field. Training of health workers on infection prevention and control, surveillance and clinical case management is ongoing. Social mobilization activities are being conducted which include the dissemination of IEC (Information Education Communication) material, sensitization on Marburg prevention and control and broadcast of information through radio channels. The first shipment of personal protective equipment (PPE) provided by WHO arrived over the weekend.
The WHO Regional office has deployed an epidemiologist and a logistician to Uganda to support the response teams on the ground. In addition, a social mobilization expert from WHO Zambia Country Office and a logistician from the Regional Rapid Response Team network have been mobilized for immediate deployment. More experts are being identified by the Global Outbreak Alert and Response Network (GOARN).
As the investigation into the outbreak continues, WHO and partners continue to support the national authorities as needed in the areas of coordination, infection prevention and control, surveillance, epidemiology, public information and social mobilization, anthropological analysis and logistics for outbreak response.
Neighbouring countries have been contacted to strengthen cross border surveillance and preparedness to prevent cross border spread of the outbreak.
WHO advises that there is no need for any restrictions on travel or trade with Uganda.
Gruß
Birgitt
31.10.2012 - WHO
As of 28 October 2012, a total of 18 cases and 9 deaths, including a health worker, have been reported from 5 districts namely Kabale district, in south-western Uganda, Kampala (the capital city), Ibanda, Mbarara and Kabarole. The case fatality rate is 50%. The outbreak was declared by the Ministry of Health in Uganda on 19 October 2012. Blood samples from 9 cases have been confirmed for Marburg virus at the Uganda Virus Research Institute (UVRI).
Currently, 13 patients have been admitted to hospital (2 in Kampala, 8 in Kabale, 3 in Ibanda) and their contacts are listed for daily follow up. The latest confirmed case was admitted to Ibanda district isolation ward on 26 October 2012.
The World Health Organization (WHO) and international partners including, the Centers for Disease Control and Prevention (CDC), the Uganda Red Cross (URCS), African Field Epidemiology Network (AFENET) and Médecins-Sans-Frontières (MSF) are supporting the national authorities in outbreak investigation and response. The national task force has identified additional health care workers and epidemiologists to strengthen the teams in the field. Training of health workers on infection prevention and control, surveillance and clinical case management is ongoing. Social mobilization activities are being conducted which include the dissemination of IEC (Information Education Communication) material, sensitization on Marburg prevention and control and broadcast of information through radio channels. The first shipment of personal protective equipment (PPE) provided by WHO arrived over the weekend.
The WHO Regional office has deployed an epidemiologist and a logistician to Uganda to support the response teams on the ground. In addition, a social mobilization expert from WHO Zambia Country Office and a logistician from the Regional Rapid Response Team network have been mobilized for immediate deployment. More experts are being identified by the Global Outbreak Alert and Response Network (GOARN).
As the investigation into the outbreak continues, WHO and partners continue to support the national authorities as needed in the areas of coordination, infection prevention and control, surveillance, epidemiology, public information and social mobilization, anthropological analysis and logistics for outbreak response.
Neighbouring countries have been contacted to strengthen cross border surveillance and preparedness to prevent cross border spread of the outbreak.
WHO advises that there is no need for any restrictions on travel or trade with Uganda.
Gruß
Birgitt
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Marburg-Fieber in Uganda | Reisehinweis
MARBURG VIRUS DISEASE - UGANDA (09): TRAVEL ADVICE, CDC
*******************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
In this post:
[1] News report
[2] CDC travel notice
******
[1] News report
Date: Sun 4 Nov 2012
Source: Examiner.com [edited]
http://www.examiner.com/article/cdc-iss ... g-outbreak
CDC issues travel notice for Uganda due to Marburg outbreak
-----------------------------------------------------------
With the Marburg virus disease outbreak spreading in Uganda, now being reported from 5 districts in the African country, [U.S.] federal health officials have issued an advisory for travelers to Uganda, according to a Centers for Disease Control and Prevention (CDC) travel notice [dated 2 Nov 2012; see below]
The Uganda Ministry of Health officially declared an outbreak on 19 Oct 2012. As of 28 Oct 2012, a total of 18 cases and 9 deaths, including a health worker, have been reported from 5 districts namely Kabale district, in southwestern Uganda, Kampala (the capital city), Ibanda, Mbarara, and Kabarole. 9 of the cases are laboratory confirmed. This represents a case-fatality rate of 50 percent. Currently, 13 patients have been admitted to hospital (2 in Kampala, 8 in Kabale, 3 in Ibanda) and their contacts are listed for daily follow up.
The CDC notes that the city of Kabale is often a stopping point for tourists visiting both Lake Bunyonyi and the Mgahinga and Bwindi Impenetrable National Parks, which are famous for mountain gorilla tracking. Although health officials are not recommending any travel restrictions at this time, and the risk for travelers is low, they do offer the following recommendations for travelers to protect themselves from Marburg [virus disease]:
- Practice good hygiene. Avoid contact with blood and body fluids of infected people. Do not handle items that may have come in contact with an infected person's blood or body fluids.
- Avoid contact with bats, such as entering bat caves.
- Avoid contact with other animals, especially monkeys.
Symptoms of Marburg virus infection include headache; muscle aches; rash on the chest, back, or stomach; nausea; vomiting; chest pain; sore throat; abdominal pain; and diarrhea. Severe symptoms include jaundice, severe weight loss, shock, massive internal bleeding, and failure of multiple internal organs.
[Byline: Robert Herriman]
--
Communicated by:
ProMED-mail from HealthMap alerts
<promed@promedmail.org>
******
[2] CDC travel notice
Date: Mon 5 Nov 2012
Source: Centers for Disease Control and Prevention (CDC) Travelers' Health [edited]
http://wwwnc.cdc.gov/travel/notices/in- ... a-2012.htm
Travel notice -- Uganda
-----------------------
What is the current situation?
------------------------------
The Ugandan Ministry of Health (MOH) has reported an outbreak of Marburg virus disease in the Kitumba subcounty of the Kabale and Ibanda Districts in southwestern Uganda. As of 28 Oct 2012, 18 cases and 9 deaths have been reported. 9 of the cases are laboratory confirmed.
The city of Kabale is within several miles of the outbreak. Kabale is often a stopping point for people visiting both Lake Bunyonyi and the Mgahinga and Bwindi Impenetrable National Parks, which are famous for mountain gorilla tracking. This city is also a transportation hub, with roads leading to both Rwanda and the Democratic Republic of the Congo. CDC is working closely with the Ugandan MOH and the World Health Organization (WHO) to control the outbreak. CDC does not recommend any travel restrictions at this time.
What is Marburg virus disease?
--------------------------
Marburg hemorrhagic fever (Marburg HF), [more precisely, Marburg virus disease], is a rare and deadly disease. The virus that causes Marburg HF is thought to be carried by African fruit bats. Scientists do not know exactly how the virus is spread from bats to humans. People have become infected by touching fluids or blood of infected people or infected monkeys. People in close contact with people who have the virus are at highest risk.
Symptoms include fever; headache; muscle aches; rash on the chest, back, or stomach; nausea; vomiting; chest pain; sore throat; abdominal pain; and diarrhea. Severe symptoms include jaundice (yellowing of skin and eyes), severe weight loss, shock, massive internal bleeding, and failure of multiple internal organs.
How can travelers protect themselves?
-------------------------------------
There is no vaccine to prevent Marburg [virus disease] and no specific treatment for people who become ill. Although travelers are at low risk for the disease, it is important to take steps to prevent Marburg HF.
- Practice good hygiene. Avoid contact with blood and body fluids of infected people. Do not handle items that may have come in contact with an infected person's blood or body fluids.
- Avoid contact with bats, such as entering bat caves.
- Avoid contact with other animals, especially monkeys.
Health care workers who may be exposed to people with the disease should follow these steps:
- Wear protective clothing, including masks, gloves, gowns, and goggles.
- Practice proper infection control and sterilization measures. For more information, see Infection Control for Viral Hemorrhagic Fevers in the African Health Care Setting at http://www.cdc.gov/ncidod/dvrd/spb/mnpa ... manual.htm).
- Isolate Marburg [virus disease] patients from unprotected persons. Also avoid direct contact with the bodies of infected deceased patients.
Clinician information
---------------------
Marburg virus disease infection is a notifiable condition in the USA. If a person with travel history to affected areas has the symptoms described above and infection with Marburg virus is suspected, isolate the patient and notify local and state health departments and CDC.
Antigen-capture enzyme-linked immunosorbent assay (ELISA) testing, IgM-capture ELISA, polymerase chain reaction (PCR), and virus isolation can be used to confirm a case of Marburg [virus disease] within a few days of the onset of symptoms. The IgG-capture ELISA is appropriate for testing persons later in the course of disease or after recovery. The disease is readily diagnosed by immunohistochemistry, virus isolation, or PCR of blood or tissue specimens from deceased patients.
There is no standard treatment for Marburg [virus disease]. Patients receive supportive therapy that consists of balancing the patient's fluids and electrolytes, maintaining their oxygen status and blood pressure, and treating them for any complicating infections.
Additional information
----------------------
Marburg Hemorrhagic Fever (CDC Viral Special Pathogens Branch):
http://www.cdc.gov/ncidod/dvrd/spb/mnpa ... urg/qa.htm
Viral Hemorrhagic Fevers (CDC Yellow Book):
http://wwwnc.cdc.gov/travel/yellowbook/ ... fevers.htm
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
[The case numbers remain unchanged from the last listing from Uganda.
A HealthMap/ProMED-mail interactive map of Uganda can be seen at http://healthmap.org/r/3LUA.
A directory listing the locations and populations of settlements in Kabale District of Uganda can be accessed at http://www.fallingrain.com/world/UG/34/. - Mod.CP]
*******************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
In this post:
[1] News report
[2] CDC travel notice
******
[1] News report
Date: Sun 4 Nov 2012
Source: Examiner.com [edited]
http://www.examiner.com/article/cdc-iss ... g-outbreak
CDC issues travel notice for Uganda due to Marburg outbreak
-----------------------------------------------------------
With the Marburg virus disease outbreak spreading in Uganda, now being reported from 5 districts in the African country, [U.S.] federal health officials have issued an advisory for travelers to Uganda, according to a Centers for Disease Control and Prevention (CDC) travel notice [dated 2 Nov 2012; see below]
The Uganda Ministry of Health officially declared an outbreak on 19 Oct 2012. As of 28 Oct 2012, a total of 18 cases and 9 deaths, including a health worker, have been reported from 5 districts namely Kabale district, in southwestern Uganda, Kampala (the capital city), Ibanda, Mbarara, and Kabarole. 9 of the cases are laboratory confirmed. This represents a case-fatality rate of 50 percent. Currently, 13 patients have been admitted to hospital (2 in Kampala, 8 in Kabale, 3 in Ibanda) and their contacts are listed for daily follow up.
The CDC notes that the city of Kabale is often a stopping point for tourists visiting both Lake Bunyonyi and the Mgahinga and Bwindi Impenetrable National Parks, which are famous for mountain gorilla tracking. Although health officials are not recommending any travel restrictions at this time, and the risk for travelers is low, they do offer the following recommendations for travelers to protect themselves from Marburg [virus disease]:
- Practice good hygiene. Avoid contact with blood and body fluids of infected people. Do not handle items that may have come in contact with an infected person's blood or body fluids.
- Avoid contact with bats, such as entering bat caves.
- Avoid contact with other animals, especially monkeys.
Symptoms of Marburg virus infection include headache; muscle aches; rash on the chest, back, or stomach; nausea; vomiting; chest pain; sore throat; abdominal pain; and diarrhea. Severe symptoms include jaundice, severe weight loss, shock, massive internal bleeding, and failure of multiple internal organs.
[Byline: Robert Herriman]
--
Communicated by:
ProMED-mail from HealthMap alerts
<promed@promedmail.org>
******
[2] CDC travel notice
Date: Mon 5 Nov 2012
Source: Centers for Disease Control and Prevention (CDC) Travelers' Health [edited]
http://wwwnc.cdc.gov/travel/notices/in- ... a-2012.htm
Travel notice -- Uganda
-----------------------
What is the current situation?
------------------------------
The Ugandan Ministry of Health (MOH) has reported an outbreak of Marburg virus disease in the Kitumba subcounty of the Kabale and Ibanda Districts in southwestern Uganda. As of 28 Oct 2012, 18 cases and 9 deaths have been reported. 9 of the cases are laboratory confirmed.
The city of Kabale is within several miles of the outbreak. Kabale is often a stopping point for people visiting both Lake Bunyonyi and the Mgahinga and Bwindi Impenetrable National Parks, which are famous for mountain gorilla tracking. This city is also a transportation hub, with roads leading to both Rwanda and the Democratic Republic of the Congo. CDC is working closely with the Ugandan MOH and the World Health Organization (WHO) to control the outbreak. CDC does not recommend any travel restrictions at this time.
What is Marburg virus disease?
--------------------------
Marburg hemorrhagic fever (Marburg HF), [more precisely, Marburg virus disease], is a rare and deadly disease. The virus that causes Marburg HF is thought to be carried by African fruit bats. Scientists do not know exactly how the virus is spread from bats to humans. People have become infected by touching fluids or blood of infected people or infected monkeys. People in close contact with people who have the virus are at highest risk.
Symptoms include fever; headache; muscle aches; rash on the chest, back, or stomach; nausea; vomiting; chest pain; sore throat; abdominal pain; and diarrhea. Severe symptoms include jaundice (yellowing of skin and eyes), severe weight loss, shock, massive internal bleeding, and failure of multiple internal organs.
How can travelers protect themselves?
-------------------------------------
There is no vaccine to prevent Marburg [virus disease] and no specific treatment for people who become ill. Although travelers are at low risk for the disease, it is important to take steps to prevent Marburg HF.
- Practice good hygiene. Avoid contact with blood and body fluids of infected people. Do not handle items that may have come in contact with an infected person's blood or body fluids.
- Avoid contact with bats, such as entering bat caves.
- Avoid contact with other animals, especially monkeys.
Health care workers who may be exposed to people with the disease should follow these steps:
- Wear protective clothing, including masks, gloves, gowns, and goggles.
- Practice proper infection control and sterilization measures. For more information, see Infection Control for Viral Hemorrhagic Fevers in the African Health Care Setting at http://www.cdc.gov/ncidod/dvrd/spb/mnpa ... manual.htm).
- Isolate Marburg [virus disease] patients from unprotected persons. Also avoid direct contact with the bodies of infected deceased patients.
Clinician information
---------------------
Marburg virus disease infection is a notifiable condition in the USA. If a person with travel history to affected areas has the symptoms described above and infection with Marburg virus is suspected, isolate the patient and notify local and state health departments and CDC.
Antigen-capture enzyme-linked immunosorbent assay (ELISA) testing, IgM-capture ELISA, polymerase chain reaction (PCR), and virus isolation can be used to confirm a case of Marburg [virus disease] within a few days of the onset of symptoms. The IgG-capture ELISA is appropriate for testing persons later in the course of disease or after recovery. The disease is readily diagnosed by immunohistochemistry, virus isolation, or PCR of blood or tissue specimens from deceased patients.
There is no standard treatment for Marburg [virus disease]. Patients receive supportive therapy that consists of balancing the patient's fluids and electrolytes, maintaining their oxygen status and blood pressure, and treating them for any complicating infections.
Additional information
----------------------
Marburg Hemorrhagic Fever (CDC Viral Special Pathogens Branch):
http://www.cdc.gov/ncidod/dvrd/spb/mnpa ... urg/qa.htm
Viral Hemorrhagic Fevers (CDC Yellow Book):
http://wwwnc.cdc.gov/travel/yellowbook/ ... fevers.htm
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
[The case numbers remain unchanged from the last listing from Uganda.
A HealthMap/ProMED-mail interactive map of Uganda can be seen at http://healthmap.org/r/3LUA.
A directory listing the locations and populations of settlements in Kabale District of Uganda can be accessed at http://www.fallingrain.com/world/UG/34/. - Mod.CP]
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Marburg-Fieber in Uganda | Ibanda
MARBURG VIRUS DISEASE - UGANDA (10); (KABALE), FATAL
****************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Sat 10 Nov 2012
Source: Saturday Monitor, National [edited]
http://www.monitor.co.ug/News/National/ ... index.html
Boy dies of Marburg virus disease in Ibanda
-------------------------------------------
A one-and-half-year old boy has reportedly died of Marburg virus infection at Ruhoko Hospital in Ibanda District. The District Health Officer, Dr Julius Bamwine, on Thursday confirmed to 'Saturday Monitor' that the victim died on Wednesday night [7 Nov 2012]. "I can confirm to you that one of the victims from Kikyenkye, who had tested positive for Marburg virus disease died last night. He was the son [of a woman] who succumbed to the same disease recently," Mr Bamwine said. The baby becomes the 2nd person from Ibanda to die [as a result of Marburg virus disease, and the 9th overall in the region to succumb to the killer virus.
The Health Ministry confirmed the Marburg virus disease outbreak a month ago in the western district of Kabale. It has since spread to 3 other districts in Western Uganda. The child's mother died of Marburg virus disease at Mbarara Regional Referral Hospital on 23 Oct 2012. Her husband had also tested positive [and survived/died ?]. The boy was admitted at Rukoho Hospital with 4 other suspected cases last week.
The number of suspected cases has since gone up to 12. Dr Bamwine said they are in the process of discharging 8 people who have tested negative while 4 still remain under surveillance as they wait for their results from Uganda Virus Research Institute in Entebbe. At Mbarara hospital, 3 suspected cases admitted last week have tested negative and have been discharged. But on Wednesday 2 more cases were admitted who exhibited symptoms similar to those of the Marburg virus disease.
"We have 2 male suspected Marburg patients; one is from Kisenyi in Kakoba Division, Mbarara Town. He had severe nasal bleeding. The other is from Rwampara County in Mbarara. He was vomiting and passed stool with blood," said Ms. Eugenia Namulindwa, the physician in-charge of the isolation unit.
Marburg [virus disease] is a rare, severe type of haemorrhagic fever which affects both humans and non-human primates. The virus is reported to be transmitted through bodily fluids like saliva and blood of an infected person, along with touching infected wild animals such as monkeys.
[Byline: Rajab Mukombozi]
--
Communicated by:
ProMED-mail from HealthMap alerts
<promed@promedmail.org>
[As of 28 Oct 2012, a total of 18 cases and 9 deaths, including a health worker, had been reported from 5 districts, namely Kabale district, in southwestern Uganda, Kampala (the capital city), Ibanda, Mbarara and Kabarole. The current report concerns the death of a child in Ibanda district, and a number of suspected but as yet unconfirmed cases. The deceased child was the son of woman who had died previously as a result of Marburg virus disease. The child's father has also tested positive for Marburg virus infection, consistent with the the fact that the majority of the confirmed cases have been family members. However there are some inconsistencies between this report and the previous one, and a clear unambiguous statement of the numbers of confirmed and suspected cases is awaited.
A HealthMap/ProMED-mail interactive map of Uganda can be seen at http://healthmap.org/r/3LUA. - Mod.CP]
****************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Sat 10 Nov 2012
Source: Saturday Monitor, National [edited]
http://www.monitor.co.ug/News/National/ ... index.html
Boy dies of Marburg virus disease in Ibanda
-------------------------------------------
A one-and-half-year old boy has reportedly died of Marburg virus infection at Ruhoko Hospital in Ibanda District. The District Health Officer, Dr Julius Bamwine, on Thursday confirmed to 'Saturday Monitor' that the victim died on Wednesday night [7 Nov 2012]. "I can confirm to you that one of the victims from Kikyenkye, who had tested positive for Marburg virus disease died last night. He was the son [of a woman] who succumbed to the same disease recently," Mr Bamwine said. The baby becomes the 2nd person from Ibanda to die [as a result of Marburg virus disease, and the 9th overall in the region to succumb to the killer virus.
The Health Ministry confirmed the Marburg virus disease outbreak a month ago in the western district of Kabale. It has since spread to 3 other districts in Western Uganda. The child's mother died of Marburg virus disease at Mbarara Regional Referral Hospital on 23 Oct 2012. Her husband had also tested positive [and survived/died ?]. The boy was admitted at Rukoho Hospital with 4 other suspected cases last week.
The number of suspected cases has since gone up to 12. Dr Bamwine said they are in the process of discharging 8 people who have tested negative while 4 still remain under surveillance as they wait for their results from Uganda Virus Research Institute in Entebbe. At Mbarara hospital, 3 suspected cases admitted last week have tested negative and have been discharged. But on Wednesday 2 more cases were admitted who exhibited symptoms similar to those of the Marburg virus disease.
"We have 2 male suspected Marburg patients; one is from Kisenyi in Kakoba Division, Mbarara Town. He had severe nasal bleeding. The other is from Rwampara County in Mbarara. He was vomiting and passed stool with blood," said Ms. Eugenia Namulindwa, the physician in-charge of the isolation unit.
Marburg [virus disease] is a rare, severe type of haemorrhagic fever which affects both humans and non-human primates. The virus is reported to be transmitted through bodily fluids like saliva and blood of an infected person, along with touching infected wild animals such as monkeys.
[Byline: Rajab Mukombozi]
--
Communicated by:
ProMED-mail from HealthMap alerts
<promed@promedmail.org>
[As of 28 Oct 2012, a total of 18 cases and 9 deaths, including a health worker, had been reported from 5 districts, namely Kabale district, in southwestern Uganda, Kampala (the capital city), Ibanda, Mbarara and Kabarole. The current report concerns the death of a child in Ibanda district, and a number of suspected but as yet unconfirmed cases. The deceased child was the son of woman who had died previously as a result of Marburg virus disease. The child's father has also tested positive for Marburg virus infection, consistent with the the fact that the majority of the confirmed cases have been family members. However there are some inconsistencies between this report and the previous one, and a clear unambiguous statement of the numbers of confirmed and suspected cases is awaited.
A HealthMap/ProMED-mail interactive map of Uganda can be seen at http://healthmap.org/r/3LUA. - Mod.CP]
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Birgitt
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Marburg-Fieber in Uganda - WHO update
Marburg haemorrhagic fever in Uganda - update
23.11.2012 - WHO
As of 23 November 2012, a total of 20 (probable or confirmed) cases, including 9 deaths have been reported from 4 districts in Uganda (Kabale, Ibanda, Mbarara, and Kampala).
The last confirmed case was hospitalised on 31 October 2012.
The Ministry of Health continues to conduct active surveillance and investigation on all cases alerted in the 4 districts. Close contacts of the Marburg cases are being followed-up for a period of 21 days.
WHO and international partners, including the US Centers for Disease Control and Prevention (CDC), the Uganda Red Cross (URCS), African Field Epidemiology Network (AFENET), Plan Uganda and Médecins Sans Frontières (MSF) are supporting the national authorities in the investigation and response to the outbreak. Experts have been deployed through the Global Outbreak Alert and Response Network (GOARN) to strengthen the field team.
Trainings are being provided to health professionals on infection prevention and control (IPC), and on field information management. Social mobilization activities are being conducted to raise awareness on prevention and control of Marburg haemorrhagic fever.
With respect to this outbreak, WHO does not recommend that any travel or trade restriction be applied to Uganda.
Gruß
Birgitt
23.11.2012 - WHO
As of 23 November 2012, a total of 20 (probable or confirmed) cases, including 9 deaths have been reported from 4 districts in Uganda (Kabale, Ibanda, Mbarara, and Kampala).
The last confirmed case was hospitalised on 31 October 2012.
The Ministry of Health continues to conduct active surveillance and investigation on all cases alerted in the 4 districts. Close contacts of the Marburg cases are being followed-up for a period of 21 days.
WHO and international partners, including the US Centers for Disease Control and Prevention (CDC), the Uganda Red Cross (URCS), African Field Epidemiology Network (AFENET), Plan Uganda and Médecins Sans Frontières (MSF) are supporting the national authorities in the investigation and response to the outbreak. Experts have been deployed through the Global Outbreak Alert and Response Network (GOARN) to strengthen the field team.
Trainings are being provided to health professionals on infection prevention and control (IPC), and on field information management. Social mobilization activities are being conducted to raise awareness on prevention and control of Marburg haemorrhagic fever.
With respect to this outbreak, WHO does not recommend that any travel or trade restriction be applied to Uganda.
Gruß
Birgitt
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Alexander
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Marburg-Fieber in Uganda | Kampala
Kampala - In Uganda ist erneut das eng mit Ebola verwandte Marburg-Fieber aufgetaucht. Ein 30-jähriger Mann sei daran gestorben, 80 Kontaktpersonen stünden in Quarantäne unter Beobachtung, teilten die Behörden in Kampala mit [...] Der am Marburg-Fieber gestorbene Mann hatte den Behördenangaben zufolge in einem christlichen Missionsspital in Kampala als Röntgenassistent gearbeitet ...
nachrichten.ch: Marburg-Fieber in Uganda ausgebrochen
Grüsse
Alexander
nachrichten.ch: Marburg-Fieber in Uganda ausgebrochen
Grüsse
Alexander
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Marburg-Fieber in Uganda - Kampala
MARBURG VIRUS DISEASE - UGANDA: (KAMPALA), REQUEST FOR INFORMATION
******************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: 5 Oct 2014
Source: Reuters [edited]
http://www.reuters.com/article/2014/10/ ... O120141005
A man has died in Uganda's capital after an outbreak of Marburg, a highly infectious hemorrhagic fever similar to Ebola, authorities said on Sunday [5 Oct 2014], adding that a total of 80 people who came into contact with him were quarantined.
Marburg starts with a severe headache followed by hemorrhaging and leads to death in 80 percent or more of cases in about 9 days. It is from the same family of viruses as Ebola, which has killed thousands in West Africa in recent months.
There is no vaccine or specific treatment for the Marburg virus, which is transmitted through bodily fluids such as saliva and blood or by handling infected wild animals such as monkeys.
The health ministry said in a statement that the 30-year-old radiographer died on 28 Sep 2014 while working at a hospital in Kampala. He had started feeling unwell about 10 days earlier, and his condition kept deteriorating. He complained of headache, abdominal pain, vomiting blood and diarrhea.
Samples were taken and tested at the Uganda Virus Research Institute, and results confirmed the man had a marburgvirus.
Doctors said his brother, one of the people he came into contact with, has developed similar symptoms and has been quarantined in a group of 80 others, 60 of whom are health workers.
Those quarantined came into contact with the victim either in Kampala or his burial place in Kasese, a district in western Uganda bordering the Democratic Republic of Congo.
Marburg has a shorter incubation period of 14 days, compared with Ebola's 21. The current outbreak of Ebola, the deadliest on record so far, has killed more than 3400 people in 4 West African countries.
Uganda has been hit by several outbreaks of Marburg and Ebola in the past, but it has contained the outbreaks quickly, limiting fatalities. Its worst occurrence of hemorrhagic fever occurred in 2000, when 425 people contracted Ebola, and more than half of them died.
[Byline: Elias Biryabarema]
--
Communicated by:
ProMED-mail Rapporteur Kunihiko Iizuka
[The following excerpts are from Mod.CP's commentary on the most recent outbreak of Marburg, which occurred in Uganda in 2012:
"The 1st outbreak of this disease occurred in Marburg, Germany, and Belgrade, former Yugoslavia, in 1967, leading to the initial recognition of this disease. The outbreak was associated with laboratory work using African green monkeys (_Cercopithecus aethiops_) imported from Uganda. Subsequently, outbreaks and sporadic cases have been reported in Angola, Democratic Republic of the Congo, Kenya, South Africa (in a person with a recent travel history to Zimbabwe) and Uganda.
Ecological studies are in progress to identify the natural reservoir of both Marburg and Ebola. There is evidence that bats are involved, but much work remains to be done to definitively describe the natural transmission cycle. Monkeys are susceptible to infection but are not considered plausible reservoir hosts, as virtually all infected animals die too rapidly to sustain survival of the virus. Infection of humans occurs sporadically."
The WHO fact sheet on Marburg (available at: http://www.who.int/mediacentre/factshee ... arburg/en/) includes the following information:
- The Marburg virus causes severe viral haemorrhagic fever in humans.
- Case fatality rates in Marburg haemorrhagic fever outbreaks have ranged from 24-88 percent.
- _Rousettus aegypti_, fruit bats of the Pteropodidae family, are considered to be natural hosts of Marburg virus. The Marburg virus is transmitted to people from fruit bats and spreads among humans through human-to-human transmission.
- No specific antiviral treatment or vaccine is available.
ProMED would welcome authoritative information on this outbreak. - Mod.LM
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/97.]
******************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: 5 Oct 2014
Source: Reuters [edited]
http://www.reuters.com/article/2014/10/ ... O120141005
A man has died in Uganda's capital after an outbreak of Marburg, a highly infectious hemorrhagic fever similar to Ebola, authorities said on Sunday [5 Oct 2014], adding that a total of 80 people who came into contact with him were quarantined.
Marburg starts with a severe headache followed by hemorrhaging and leads to death in 80 percent or more of cases in about 9 days. It is from the same family of viruses as Ebola, which has killed thousands in West Africa in recent months.
There is no vaccine or specific treatment for the Marburg virus, which is transmitted through bodily fluids such as saliva and blood or by handling infected wild animals such as monkeys.
The health ministry said in a statement that the 30-year-old radiographer died on 28 Sep 2014 while working at a hospital in Kampala. He had started feeling unwell about 10 days earlier, and his condition kept deteriorating. He complained of headache, abdominal pain, vomiting blood and diarrhea.
Samples were taken and tested at the Uganda Virus Research Institute, and results confirmed the man had a marburgvirus.
Doctors said his brother, one of the people he came into contact with, has developed similar symptoms and has been quarantined in a group of 80 others, 60 of whom are health workers.
Those quarantined came into contact with the victim either in Kampala or his burial place in Kasese, a district in western Uganda bordering the Democratic Republic of Congo.
Marburg has a shorter incubation period of 14 days, compared with Ebola's 21. The current outbreak of Ebola, the deadliest on record so far, has killed more than 3400 people in 4 West African countries.
Uganda has been hit by several outbreaks of Marburg and Ebola in the past, but it has contained the outbreaks quickly, limiting fatalities. Its worst occurrence of hemorrhagic fever occurred in 2000, when 425 people contracted Ebola, and more than half of them died.
[Byline: Elias Biryabarema]
--
Communicated by:
ProMED-mail Rapporteur Kunihiko Iizuka
[The following excerpts are from Mod.CP's commentary on the most recent outbreak of Marburg, which occurred in Uganda in 2012:
"The 1st outbreak of this disease occurred in Marburg, Germany, and Belgrade, former Yugoslavia, in 1967, leading to the initial recognition of this disease. The outbreak was associated with laboratory work using African green monkeys (_Cercopithecus aethiops_) imported from Uganda. Subsequently, outbreaks and sporadic cases have been reported in Angola, Democratic Republic of the Congo, Kenya, South Africa (in a person with a recent travel history to Zimbabwe) and Uganda.
Ecological studies are in progress to identify the natural reservoir of both Marburg and Ebola. There is evidence that bats are involved, but much work remains to be done to definitively describe the natural transmission cycle. Monkeys are susceptible to infection but are not considered plausible reservoir hosts, as virtually all infected animals die too rapidly to sustain survival of the virus. Infection of humans occurs sporadically."
The WHO fact sheet on Marburg (available at: http://www.who.int/mediacentre/factshee ... arburg/en/) includes the following information:
- The Marburg virus causes severe viral haemorrhagic fever in humans.
- Case fatality rates in Marburg haemorrhagic fever outbreaks have ranged from 24-88 percent.
- _Rousettus aegypti_, fruit bats of the Pteropodidae family, are considered to be natural hosts of Marburg virus. The Marburg virus is transmitted to people from fruit bats and spreads among humans through human-to-human transmission.
- No specific antiviral treatment or vaccine is available.
ProMED would welcome authoritative information on this outbreak. - Mod.LM
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/97.]
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Birgitt
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Marburg-Fieber in Uganda
MARBURG VIRUS DISEASE - UGANDA (02): SUSPECTED CASES
****************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
In this report:
[1] Additional suspected cases
[2] Media reports
[3] Uganda MOH official report
*****
[1] Additional suspected cases
Date: 6 Oct 2014
Source: NTV News (Uganda) [edited]
http://www.ntvuganda.co.ug/news/local/0 ... e-suspects
Ministry of Health monitoring Marburg disease suspects
---------------------------------------------------------------
The ministry of health has confirmed that there are 8 suspected cases of the Marburg Viral Disease from in Uganda from Kasese, Mpigi and Kampala districts. The 8 including the brother of the 1st victim to the disease who died in September [2014] are exhibiting mild signs and symptoms of the deadly viral disease.
Marburg viruses are endemic in arid woodlands of equatorial Africa and have been found in monkeys, chimps and fruit bats.
Experts suspect that the marburg virus is transmitted to humans through an infected animal's bodily fluids including blood and through the droppings or urine of bats.
--
Communicated by:
ProMED-mail Rapporteur Kunihiko Iizuka
******
[2] Media report
Date: 5 Oct 2014
Source: Forbes [Edited]
http://www.forbes.com/sites/davidkroll/ ... -relative/
Ugandan Health Worker Dies Of Marburg Virus, Ebola Relative
-----------------------------------------------------------------------
The Ugandan Ministry of Health is reporting today that a 30-year-old male health care worker died of Marburg hemorrhagic fever on [30 Sep2014].
The gentleman had been a radiographer, or X-ray technician, at the Mpigi Health Centre IV, but was recruited 2 months ago for a similar position at Mengo Hospital, about 20 miles (33 km) away. When he felt ill on [17 Sep 2014], he traveled back to Mpigi for treatment since "he felt more comfortable with a facility that he had worked with for a long time."
Today's [6 Oct 2014] statement from Elioda Tumwesigye, Minister of State for General Duties & Holding the Portfolio of Minister for Health, describes a total of 80 people who were in contact with the man have been identified and isolated to follow for signs and symptoms during the 21-day incubation period, the same incubation period for Ebola.
Most concerning is that 38 of the contacts are health care workers from Mengo Hospital, including the man's brother, and 22 health care workers from Mpigi Health Center IV. The remaining 20 contacts are residents of the Kasese district.
The official reports that the man's brother has already developed signs consistent with Marburg infection. He has been quarantined and isolated for further monitoring while his blood samples are being analyzed at the Uganda Virus Research Institute.
[Byline: David Kroll]
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
******
[3] Uganda MOH Official Report
Date: 4 Oct 2013
Source: Ministry of Health, Uganda, Weekly Epidemiologic Bulletin, Epidemiological week 37 of 2014 [8th September- 14th September 2014] [edited]
http://health.go.ug/mohweb/?page_id=1294 [currently the week 37 Bulletin is not yet available at this website, it was sent by email to ProMED-mail]
Suspected Marburg Outbreak, Mpigi:
On [3 Oct 2014], UVRI/CDC Viral Haemorrhagic Fever Reference Laboratory in Entebbe released preliminary results of a sample that was obtained from a patient in a private Hospital in Kampala. The patient was a 30 year old male Health Worker, who fell sick on (or around) [18 Sep 2014]. He was admitted to a HC IV in Mpigi District and later transferred to a private Hospital in Kampala. He died on [28 Sep 2014] and was buried in Kasese on [30 Sep 2014]. There were multiple contacts in the two health facilities that interacted with this suspected Marburg case, and also in the process of burial in Kasese. CDC will shortly communicate the results of the retesting.
--
Communicated by:
Robert Musoke, MD.
Senior Epidemiologist
Resource Centre,
Ministry of Health-Uganda
<robert.musoke@gmail.com>
[The announcements of 8 suspected cases and the disclosure of numerous contacts that include many health care workers are indeed worrisome developments.
Mpigi is a town approximately 37 km west of Kampala. Kasese, the burial site of the fatal case, is located approximately 360 km west of Kampala, near the Congo DR border.
A ProMED/HealthMap is available at: http://healthmap.org/promed/p/97. - Mod.LM]
****************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
In this report:
[1] Additional suspected cases
[2] Media reports
[3] Uganda MOH official report
*****
[1] Additional suspected cases
Date: 6 Oct 2014
Source: NTV News (Uganda) [edited]
http://www.ntvuganda.co.ug/news/local/0 ... e-suspects
Ministry of Health monitoring Marburg disease suspects
---------------------------------------------------------------
The ministry of health has confirmed that there are 8 suspected cases of the Marburg Viral Disease from in Uganda from Kasese, Mpigi and Kampala districts. The 8 including the brother of the 1st victim to the disease who died in September [2014] are exhibiting mild signs and symptoms of the deadly viral disease.
Marburg viruses are endemic in arid woodlands of equatorial Africa and have been found in monkeys, chimps and fruit bats.
Experts suspect that the marburg virus is transmitted to humans through an infected animal's bodily fluids including blood and through the droppings or urine of bats.
--
Communicated by:
ProMED-mail Rapporteur Kunihiko Iizuka
******
[2] Media report
Date: 5 Oct 2014
Source: Forbes [Edited]
http://www.forbes.com/sites/davidkroll/ ... -relative/
Ugandan Health Worker Dies Of Marburg Virus, Ebola Relative
-----------------------------------------------------------------------
The Ugandan Ministry of Health is reporting today that a 30-year-old male health care worker died of Marburg hemorrhagic fever on [30 Sep2014].
The gentleman had been a radiographer, or X-ray technician, at the Mpigi Health Centre IV, but was recruited 2 months ago for a similar position at Mengo Hospital, about 20 miles (33 km) away. When he felt ill on [17 Sep 2014], he traveled back to Mpigi for treatment since "he felt more comfortable with a facility that he had worked with for a long time."
Today's [6 Oct 2014] statement from Elioda Tumwesigye, Minister of State for General Duties & Holding the Portfolio of Minister for Health, describes a total of 80 people who were in contact with the man have been identified and isolated to follow for signs and symptoms during the 21-day incubation period, the same incubation period for Ebola.
Most concerning is that 38 of the contacts are health care workers from Mengo Hospital, including the man's brother, and 22 health care workers from Mpigi Health Center IV. The remaining 20 contacts are residents of the Kasese district.
The official reports that the man's brother has already developed signs consistent with Marburg infection. He has been quarantined and isolated for further monitoring while his blood samples are being analyzed at the Uganda Virus Research Institute.
[Byline: David Kroll]
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
******
[3] Uganda MOH Official Report
Date: 4 Oct 2013
Source: Ministry of Health, Uganda, Weekly Epidemiologic Bulletin, Epidemiological week 37 of 2014 [8th September- 14th September 2014] [edited]
http://health.go.ug/mohweb/?page_id=1294 [currently the week 37 Bulletin is not yet available at this website, it was sent by email to ProMED-mail]
Suspected Marburg Outbreak, Mpigi:
On [3 Oct 2014], UVRI/CDC Viral Haemorrhagic Fever Reference Laboratory in Entebbe released preliminary results of a sample that was obtained from a patient in a private Hospital in Kampala. The patient was a 30 year old male Health Worker, who fell sick on (or around) [18 Sep 2014]. He was admitted to a HC IV in Mpigi District and later transferred to a private Hospital in Kampala. He died on [28 Sep 2014] and was buried in Kasese on [30 Sep 2014]. There were multiple contacts in the two health facilities that interacted with this suspected Marburg case, and also in the process of burial in Kasese. CDC will shortly communicate the results of the retesting.
--
Communicated by:
Robert Musoke, MD.
Senior Epidemiologist
Resource Centre,
Ministry of Health-Uganda
<robert.musoke@gmail.com>
[The announcements of 8 suspected cases and the disclosure of numerous contacts that include many health care workers are indeed worrisome developments.
Mpigi is a town approximately 37 km west of Kampala. Kasese, the burial site of the fatal case, is located approximately 360 km west of Kampala, near the Congo DR border.
A ProMED/HealthMap is available at: http://healthmap.org/promed/p/97. - Mod.LM]
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Birgitt
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Marburg-Fieber in Uganda | Keine neuen Fälle
MARBURG VIRUS DISEASE - UGANDA (03): NO NEW CASES
*************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Tue 7 Oct 2014
Source: WMUR, CNN report [edited]
http://www.wmur.com/health/99-in-isolat ... h/28997288
99 in isolation after Uganda Marburg death; outbreak shows how contagion can be successfully contained
--------------------------------------------------------------------------------
Three days after a fatal case of Marburg hemorrhagic fever was diagnosed in Uganda, 99 people are under isolation in 4 different locations across the East African country, as field epidemiologists and surveillance officers continue to closely monitor all people who got into contact with only victim.
More than 60 health workers form the bulk of people under isolation after they were identified as having contact with a 30-year old male health worker who died [28 Sep 2014] of Marburg -- an Ebola-like hemorrhagic fever.
"As of today [7 Oct 2014], a total of 99 contacts are under follow up. All the contacts are still in a healthy condition," Dr. Jane Ruth Aceng, director general for health services in Uganda, said in the latest update on the outbreak on Tuesday.
"The National Taskforce through the field epidemiologists and surveillance officers continues to closely monitor all people who got into contact with this confirmed case," she noted.
The dead health worker was a radiographer in a hospital in the capital of Kampala and also at Mpigi District Health Center IV, places where authorities say he made contact with colleagues.
Aceng revealed that at least 11 people have tested negative after results from Uganda Virus Research Institute (UVRI) indicate that although the suspects had developed signs and symptoms similar to that of the disease, they did not contract the virus.
"However, for those who continue to have signs, tests will be run again after 3 days," Aceng said.
Among those who tested negative include are the brother of the deceased; 2 health workers from a children HIV/AIDS hospital; 7 persons from Mpigi Health Center IV; and 2 relatives of the deceased who participated in the burial.
"When he felt ill on [17 Sep 2014], he traveled back to Mpigi for treatment since he felt more comfortable with a facility that he had worked with for a long time, a duration the disease was spread," said a statement by health authorities last Sunday.
Marburg virus was 1st identified in 1967, when 31 people became sick in Germany and Yugoslavia in an outbreak that was eventually traced back to laboratory monkeys imported from Uganda. Since then the virus has appeared sporadically, with just a dozen outbreaks on record, many -- including the current situation -- involving just a single patient.
Marburg virus causes symptoms similar to Ebola, beginning with fever and weakness and often leading to internal or external bleeding, organ failure and death. The death rate runs as high as 80 percent, although it was significantly lower in the initial outbreak when patients were cared for in relatively modern, European hospitals.
The most recent outbreak, also in Uganda, in 2012, killed 4 out of 15 patients, according to the Centers for Disease Control and Prevention.
On Tuesday [7 Oct 2014], CDC Director Thomas Frieden pointed to the most recent Marburg case as an example of how a deadly virus could be contained.
"We've done important work in Uganda to help the Ugandans better have a laboratory network so they can find cases, have a response network with disease detectives who can follow up and have an emergency operations center to trace individual cases," Frieden said.
The extensive contact tracing included tracking an embalmer back to Kenya, where he was tested and found not to be infected with Marburg.
"I mention this, because oftentimes in public health, what gets noticed is what happens and it's hard to see what doesn't happen," Frieden continued, noting that there have so far been no additional cases. "That may not make headlines, but it does give us confidence that we can control Ebola in West Africa."
[Byline: Samson Ntale]
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
[Fortunately, none of at least 11 suspected cases have confirmed Marburg infection, according to the above media report. It has not yet been 21 days, the maximum expected incubation period for Marburg virus disease, since the index patient's death on 28 Sep 2014, so it is too early to declare victory. Nonetheless, it is encouraging that no new cases have emerged, attributable, as Dr. Frieden stated, to good public health, the nature of Marburg virus disease (which has resulted in generally smaller outbreaks than Ebola virus) and perhaps some good luck. - Mod.LM
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/97.]
*************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Tue 7 Oct 2014
Source: WMUR, CNN report [edited]
http://www.wmur.com/health/99-in-isolat ... h/28997288
99 in isolation after Uganda Marburg death; outbreak shows how contagion can be successfully contained
--------------------------------------------------------------------------------
Three days after a fatal case of Marburg hemorrhagic fever was diagnosed in Uganda, 99 people are under isolation in 4 different locations across the East African country, as field epidemiologists and surveillance officers continue to closely monitor all people who got into contact with only victim.
More than 60 health workers form the bulk of people under isolation after they were identified as having contact with a 30-year old male health worker who died [28 Sep 2014] of Marburg -- an Ebola-like hemorrhagic fever.
"As of today [7 Oct 2014], a total of 99 contacts are under follow up. All the contacts are still in a healthy condition," Dr. Jane Ruth Aceng, director general for health services in Uganda, said in the latest update on the outbreak on Tuesday.
"The National Taskforce through the field epidemiologists and surveillance officers continues to closely monitor all people who got into contact with this confirmed case," she noted.
The dead health worker was a radiographer in a hospital in the capital of Kampala and also at Mpigi District Health Center IV, places where authorities say he made contact with colleagues.
Aceng revealed that at least 11 people have tested negative after results from Uganda Virus Research Institute (UVRI) indicate that although the suspects had developed signs and symptoms similar to that of the disease, they did not contract the virus.
"However, for those who continue to have signs, tests will be run again after 3 days," Aceng said.
Among those who tested negative include are the brother of the deceased; 2 health workers from a children HIV/AIDS hospital; 7 persons from Mpigi Health Center IV; and 2 relatives of the deceased who participated in the burial.
"When he felt ill on [17 Sep 2014], he traveled back to Mpigi for treatment since he felt more comfortable with a facility that he had worked with for a long time, a duration the disease was spread," said a statement by health authorities last Sunday.
Marburg virus was 1st identified in 1967, when 31 people became sick in Germany and Yugoslavia in an outbreak that was eventually traced back to laboratory monkeys imported from Uganda. Since then the virus has appeared sporadically, with just a dozen outbreaks on record, many -- including the current situation -- involving just a single patient.
Marburg virus causes symptoms similar to Ebola, beginning with fever and weakness and often leading to internal or external bleeding, organ failure and death. The death rate runs as high as 80 percent, although it was significantly lower in the initial outbreak when patients were cared for in relatively modern, European hospitals.
The most recent outbreak, also in Uganda, in 2012, killed 4 out of 15 patients, according to the Centers for Disease Control and Prevention.
On Tuesday [7 Oct 2014], CDC Director Thomas Frieden pointed to the most recent Marburg case as an example of how a deadly virus could be contained.
"We've done important work in Uganda to help the Ugandans better have a laboratory network so they can find cases, have a response network with disease detectives who can follow up and have an emergency operations center to trace individual cases," Frieden said.
The extensive contact tracing included tracking an embalmer back to Kenya, where he was tested and found not to be infected with Marburg.
"I mention this, because oftentimes in public health, what gets noticed is what happens and it's hard to see what doesn't happen," Frieden continued, noting that there have so far been no additional cases. "That may not make headlines, but it does give us confidence that we can control Ebola in West Africa."
[Byline: Samson Ntale]
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
[Fortunately, none of at least 11 suspected cases have confirmed Marburg infection, according to the above media report. It has not yet been 21 days, the maximum expected incubation period for Marburg virus disease, since the index patient's death on 28 Sep 2014, so it is too early to declare victory. Nonetheless, it is encouraging that no new cases have emerged, attributable, as Dr. Frieden stated, to good public health, the nature of Marburg virus disease (which has resulted in generally smaller outbreaks than Ebola virus) and perhaps some good luck. - Mod.LM
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/97.]
-
Birgitt
- Moderator
- Beiträge: 35199
- Registriert: Di 2. Aug 2005, 22:52
- Wohnort: NRW / Südl. Rheinland
- Kontaktdaten:
Marburg-Fieber in Uganda
MARBURG VIRUS DISEASE - UGANDA (04): WHO
****************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Fri 10 Oct 2014
Source: WHO Global Alert and Response (GAR), Disease Outbreak News (DONs) [edited]
http://www.who.int/csr/don/10-october-2014-marburg/en/
Marburg virus disease -- Uganda
-------------------------------
On 5 Oct 2014, the Ministry of Health (MoH) of Uganda notified WHO of a confirmed case of Marburg virus disease (MVD) in Kampala, Uganda.
The confirmed case was a healthcare worker who had onset of disease on 11 Sep 2014 while working at Mengo Hospital, Kampala. The case presented to Mpigi District Health Center on 17 Sep 2014, and transferred to Mengo Hospital, Kampala, on 23 Sep 2014. On admission the case presented with symptoms including fever, headache, abdominal pain, vomiting and diarrhoea, and died on 28 Sep 2014.
The case reported no history of travel beyond Mpigi, no contact with a person with similar illness. He had not eaten bush meat nor had had contact with bats in the last 4 weeks.
A preliminary result indicating the specimen taken from the patient was positive for Marburg virus disease was received on 3 Oct 2014, and further confirmed on 4 Oct 2014 by the Uganda Virus Research Institute (UVRI).
As of today [10 Oct 2014], a total of 146 contacts have been identified and are being monitored for signs and symptoms compatible with MVD. 11 of the contacts developed signs and symptoms compatible with Marburg virus disease. All samples from symptomatic contacts have tested negative so far. 2nd samples have been taken from them and are being tested at the Uganda Virus Research Institute (UVRI). One contact, Kenyan mortician who travelled back to Kenya, developed a fever and cough but tested negative for both Marburg and Ebola virus. The contact in Kenya continues to be followed up by the Kenyan Rapid Response Team.
Public health response
----------------------
The Ministry of Health of Uganda has activated the National Task Force, which is meeting regularly, and sub-committees have been established.
WHO, Medecins Sans Frontieres (MSF), and the US Centers for Disease Control (CDC) are supporting the national Ugandan authorities in the investigation and response operations, including enhancements and establishment of isolation and treatment units, prepositioning personal protective equipment (PPE), and training health workers on infection control and prevention, as well as in case management and social mobilization.
Four multi-disciplinary teams have been deployed to perform an in-depth risk assessment. Surveillance and contact tracing, and follow-up activities are currently being implemented in Kampala, Mpigi and Kasese.
WHO recommendations
-------------------
Marburg virus disease is a severe and highly fatal disease caused by a virus from the same family as the one that causes Ebola virus disease. Both viruses can cause large outbreaks such as the ongoing Ebola virus disease outbreak in West Africa. The last outbreak of MVD in Uganda occurred in 2012, during which 20 cases, including 9 fatal cases, were reported from Kabale District, Kampala, Ibanda, Mbarara, and Kabarole.
WHO advises against the application of any travel or trade restrictions on Uganda based on the current information available on this outbreak.
--
Communicated by:
ProMED-EAFR
<promed-eafr@promedmail.org>
[To quote Mod.JFW's commentary:
"The detection of the initial Marburg virus disease in the current outbreak in Uganda shows a sensitive disease surveillance system that has been tested several times previously and hence the vigilance in detecting, reporting, and investigating suspect viral hemorrhagic fever cases. However, since the initial case reported in the current outbreak is a health care worker, this suggests nosocomial exposure to a source case that has not been identified. Epidemiological investigations should therefore focus on identifying the source case as this could possibly represent another chain of transmission that is yet to be identified.
Maps of Uganda can be accessed at http://en.wikipedia.org/wiki/Districts_of_Uganda and http://healthmap.org/promed/p/2470.
It is certainly possible that the only known case in the current event, a healthcare worker, was not the index case. However, one hopes that another chain of transmission, if ongoing, would have become apparent by now. - Mod.LM]
****************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Fri 10 Oct 2014
Source: WHO Global Alert and Response (GAR), Disease Outbreak News (DONs) [edited]
http://www.who.int/csr/don/10-october-2014-marburg/en/
Marburg virus disease -- Uganda
-------------------------------
On 5 Oct 2014, the Ministry of Health (MoH) of Uganda notified WHO of a confirmed case of Marburg virus disease (MVD) in Kampala, Uganda.
The confirmed case was a healthcare worker who had onset of disease on 11 Sep 2014 while working at Mengo Hospital, Kampala. The case presented to Mpigi District Health Center on 17 Sep 2014, and transferred to Mengo Hospital, Kampala, on 23 Sep 2014. On admission the case presented with symptoms including fever, headache, abdominal pain, vomiting and diarrhoea, and died on 28 Sep 2014.
The case reported no history of travel beyond Mpigi, no contact with a person with similar illness. He had not eaten bush meat nor had had contact with bats in the last 4 weeks.
A preliminary result indicating the specimen taken from the patient was positive for Marburg virus disease was received on 3 Oct 2014, and further confirmed on 4 Oct 2014 by the Uganda Virus Research Institute (UVRI).
As of today [10 Oct 2014], a total of 146 contacts have been identified and are being monitored for signs and symptoms compatible with MVD. 11 of the contacts developed signs and symptoms compatible with Marburg virus disease. All samples from symptomatic contacts have tested negative so far. 2nd samples have been taken from them and are being tested at the Uganda Virus Research Institute (UVRI). One contact, Kenyan mortician who travelled back to Kenya, developed a fever and cough but tested negative for both Marburg and Ebola virus. The contact in Kenya continues to be followed up by the Kenyan Rapid Response Team.
Public health response
----------------------
The Ministry of Health of Uganda has activated the National Task Force, which is meeting regularly, and sub-committees have been established.
WHO, Medecins Sans Frontieres (MSF), and the US Centers for Disease Control (CDC) are supporting the national Ugandan authorities in the investigation and response operations, including enhancements and establishment of isolation and treatment units, prepositioning personal protective equipment (PPE), and training health workers on infection control and prevention, as well as in case management and social mobilization.
Four multi-disciplinary teams have been deployed to perform an in-depth risk assessment. Surveillance and contact tracing, and follow-up activities are currently being implemented in Kampala, Mpigi and Kasese.
WHO recommendations
-------------------
Marburg virus disease is a severe and highly fatal disease caused by a virus from the same family as the one that causes Ebola virus disease. Both viruses can cause large outbreaks such as the ongoing Ebola virus disease outbreak in West Africa. The last outbreak of MVD in Uganda occurred in 2012, during which 20 cases, including 9 fatal cases, were reported from Kabale District, Kampala, Ibanda, Mbarara, and Kabarole.
WHO advises against the application of any travel or trade restrictions on Uganda based on the current information available on this outbreak.
--
Communicated by:
ProMED-EAFR
<promed-eafr@promedmail.org>
[To quote Mod.JFW's commentary:
"The detection of the initial Marburg virus disease in the current outbreak in Uganda shows a sensitive disease surveillance system that has been tested several times previously and hence the vigilance in detecting, reporting, and investigating suspect viral hemorrhagic fever cases. However, since the initial case reported in the current outbreak is a health care worker, this suggests nosocomial exposure to a source case that has not been identified. Epidemiological investigations should therefore focus on identifying the source case as this could possibly represent another chain of transmission that is yet to be identified.
Maps of Uganda can be accessed at http://en.wikipedia.org/wiki/Districts_of_Uganda and http://healthmap.org/promed/p/2470.
It is certainly possible that the only known case in the current event, a healthcare worker, was not the index case. However, one hopes that another chain of transmission, if ongoing, would have become apparent by now. - Mod.LM]
-
Birgitt
- Moderator
- Beiträge: 35199
- Registriert: Di 2. Aug 2005, 22:52
- Wohnort: NRW / Südl. Rheinland
- Kontaktdaten:
Marburg-Fieber in Uganda
MARBURG VIRUS DISEASE - UGANDA (05): SITUATIONAL UPDATE, NEW PROBABLE CASES
***************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: 14 Oct 2014
Source: National Marburg Hemorrhagic Fever Outbreak Situation Report (Sit Rep No. 8 ) [submitted to ProMED via email, edited]
[A Table of summary statistics is included and not reproduced here. - Mod.LM]
Highlights of the day
-------------------
No new Marburg confirmed case since detection of the index case; one probable case in Kampala admitted at Mulago isolation unit on 14 Oct 2014, and one probable case admitted in Mpigi HC IV on 14 Oct 2014.
Situation Update:
Coordination
-------------
Kampala
- NTF held meeting on 13 Oct 2014; decision made to hold NTF meetings 3 times a week (Monday, Wednesday, Friday) at 11.00 a.m.
- The VHF Preparedness and Response plan was updated in accordance with comments from MoH top management and will be presented to Cabinet, together with the Incident Plan, on Wed 15 Oct 2014 for consideration for funding.
Mpigi
- District Task Force meeting held
Kasese
- District Task Force held meeting on Tue 14 Oct 2014
Epidemiology/Surveillance/Laboratory
-----------------------------------
Kampala
- One Marburg probable case was admitted at Mulago Isolation unit on 14 Oct 2014. The case is a male aged 22 and a resident of Nalumunye in Rubaga division in Kampala. He was reportedly admitted on the same ward in Mengo hospital with the index case; his last date of contact was 28 Sep 2014. He was reported to have developed fever, headache, general body weakness and dizziness 4 days ago (around Fri 11 Oct 2014). A blood sample was taken to UVRI for laboratory investigation. Line listing of contacts is ongoing. 79 out of 93 (85 percent) of contacts were followed up, only one was reported ill as mentioned above.
- The alert case that was reported by a doctor in Mengo hospital on 12 Oct 2014 was not traced. The surveillance team is still trying to trace him.
- Investigation of source of infection of index case still ongoing Mpigi.
- 11/25 contacts were followed up.
- One of the contacts developed fever and is being monitored at HCIV; a specimen will be collected and transported to UVRI laboratory on 15 Oct 2014.
- Data harmonization is ongoing.
Kasese
- 53 of the 70 contacts (76 percent) were reached on 14 Oct 2014, and none of them were reported to be having symptoms.
- The team could not establish links with one contact who is reported to have traveled to DRC.
Case management
-----------------
Kampala
- One probable case on the ward in Mulago and one probable case in Entebbe isolation facility, pending laboratory results.
Situation Update
----------------
- Health workers in Mulago fear to attend to patients with any bleeding, considering all of them as suspected Marburg. NTF agreed that all patients should go through Triage at Mulago assessment center, and only cases meeting Marburg case definition should be referred to isolation facility. The rest should be given good medical care.
Mpigi
- A probable case admitted on 14 Oct 2014 is being monitored at Mpigi HC IV. Blood sample tested was negative for malaria, brucellosis, and typhoid.
- Turn up of patients at Mpigi HCIV has increased as the health workers also increase following their completion of the 21 days.
- There is urgent need to equip lower level health facilities with information, some PPEs and other supplies to enable them to confidently manage alert cases.
Kasese
- Currently, no patient is admitted in the isolation unit.
- MOH, WHO and Makerere University School of Public Health conducted a training of health workers on VHF preparedness, response and case management and infection prevention and control. Health workers trained were from Kilembe, Bweera and Kagando hospitals and Bukonzo West health sub-District.
Social mobilization
-------------------
Kampala
- Radio spot messages continue to run on 26 local FM radio stations.
- TV spots on Ebola and Marburg on 4 TV stations (WBS, UBC, NTV, NBS)
- Plan is underway to deploy film van in 8 districts of Kampala, Mukono, Wakiso, Mpigi, Ibanda, Kamwengye, Kasese and Bundibugyo, with support from UNICEF.
- The process of printing of IEC materials is ongoing, with support from UNICEF Mpigi.
- Use of community megaphone/community radios was encouraged because it is cheaper and has a wider coverage.
- Sensitization has only been done in Mpigi T/C; scaling up to the rest of the sub counties requires budget support from MOH.
- The CAO will appeal to the DEO to communicate with all the head teachers so that they disseminate messages on Marburg to the school-going children.
- World vision pledged to support another talk show on Saturday [18 Oct 2014] at CBS if technical officers at the district and MOH are available.
- World Vision will also pay for radio spot messages if MOH can prepare and submit them to their office.
- There is still a gap in the IEC materials.
Kasese
- Radio spots and talks shows are ongoing on local FM radios.
Psychosocial Support
----------------------
Kampala
- Psychosocial team is planning to link up with the contact tracing team and provide psychosocial support for contacts identified to be in need of the service.
- The team was requested to prioritize provision of psychosocial support to the health workers in Mengo hospital, especially those that were contacts.
Logistics
------
- Mpigi CAO submitted the district Marburg response budget to MOH.
- VHF Preparedness and Response plan to be presented to Cabinet for resource mobilization for required logistics.
Challenges/Gaps
--------------
- Inaccurate media reports, e.g. Monitor report on 13 Oct 2014, indicating that Uganda has been declared Marburg free could hamper the response activities.
- Some contacts in Kampala leave their homes and switch off their telephones making it difficult for them to be contacted and traced.
- Some contacts travel to other districts and to DRC, posing a risk of spread to other districts and countries in case they fall ill with Marburg.
- Delayed release of funds for district response activities
- Several health workers require training and orientation.
- Shortage of funds for critical response activities
- Fear among health workers in dealing with VHF patients
Planned Activities
-----------------
- A Press conference has been scheduled for 2:30 pm on 15 Oct 2014 by Mpigi district and will involve the RDC, LCV chairman, the CAO and DHO.
- Mobilization of resources for the District Response Plans
- Train health workers in the various health facilities in Kampala on VHF.
- Strengthen surveillance nationwide, especially in Kampala, Kasese, Mpigi, Wakiso, Ibanda, and Kamwenge.
- Continue investigations for the source of exposure for the index case.
- Equip the Kagando Isolation Facility.
- Train and deploy additional contact tracers in Kasese district.
Partners Involved
----------------
Ministry of Health WHO
UNICEF
MSF
KCCA, Kasese District Local Government, Mpigi District Local Government CDC
Uganda Red Cross
Conservation for Public Health
College of Veterinary, Animal Health and Bio Security (COVAB) Global Health Security
World Vision
Uganda Prisons Services
Note: This Situation Report has been developed by the National Task Force. For further clarification, contact Dr. Jane Ruth Aceng (DGHS)/(Chairperson, NTF), 0772664690,
Dr. Francis Adatu (ACHS/ESD) 0772999668,
Dr. Issa Makumbi (Manager, Emergency Operations Centre) 0750996034.
--
Communicated by:
Refaya Ndyamuba
<rndyamuba@gmail.com>
[To reiterate, there appear to be no new confirmed cases but 2 new probable cases, one in Kampala and one in Mpigi. The original report also contains a table, which we are unable to reproduce here, with details of numbers of contacts traced by region. It notes 192 possible contacts, 49 of whom are healthcare workers. Considerable contact tracing is ongoing, since the onset of the (apparent) index case on 11 Sep 2014 and his death on 28 Sep 2014. Today, 15 Oct 2014, marks day 17 since the last possible contact, nearing the extreme end of a 21-day possible incubation period. We await results of laboratory testing with great interest. - Mod.LM
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/97.]
***************************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: 14 Oct 2014
Source: National Marburg Hemorrhagic Fever Outbreak Situation Report (Sit Rep No. 8 ) [submitted to ProMED via email, edited]
[A Table of summary statistics is included and not reproduced here. - Mod.LM]
Highlights of the day
-------------------
No new Marburg confirmed case since detection of the index case; one probable case in Kampala admitted at Mulago isolation unit on 14 Oct 2014, and one probable case admitted in Mpigi HC IV on 14 Oct 2014.
Situation Update:
Coordination
-------------
Kampala
- NTF held meeting on 13 Oct 2014; decision made to hold NTF meetings 3 times a week (Monday, Wednesday, Friday) at 11.00 a.m.
- The VHF Preparedness and Response plan was updated in accordance with comments from MoH top management and will be presented to Cabinet, together with the Incident Plan, on Wed 15 Oct 2014 for consideration for funding.
Mpigi
- District Task Force meeting held
Kasese
- District Task Force held meeting on Tue 14 Oct 2014
Epidemiology/Surveillance/Laboratory
-----------------------------------
Kampala
- One Marburg probable case was admitted at Mulago Isolation unit on 14 Oct 2014. The case is a male aged 22 and a resident of Nalumunye in Rubaga division in Kampala. He was reportedly admitted on the same ward in Mengo hospital with the index case; his last date of contact was 28 Sep 2014. He was reported to have developed fever, headache, general body weakness and dizziness 4 days ago (around Fri 11 Oct 2014). A blood sample was taken to UVRI for laboratory investigation. Line listing of contacts is ongoing. 79 out of 93 (85 percent) of contacts were followed up, only one was reported ill as mentioned above.
- The alert case that was reported by a doctor in Mengo hospital on 12 Oct 2014 was not traced. The surveillance team is still trying to trace him.
- Investigation of source of infection of index case still ongoing Mpigi.
- 11/25 contacts were followed up.
- One of the contacts developed fever and is being monitored at HCIV; a specimen will be collected and transported to UVRI laboratory on 15 Oct 2014.
- Data harmonization is ongoing.
Kasese
- 53 of the 70 contacts (76 percent) were reached on 14 Oct 2014, and none of them were reported to be having symptoms.
- The team could not establish links with one contact who is reported to have traveled to DRC.
Case management
-----------------
Kampala
- One probable case on the ward in Mulago and one probable case in Entebbe isolation facility, pending laboratory results.
Situation Update
----------------
- Health workers in Mulago fear to attend to patients with any bleeding, considering all of them as suspected Marburg. NTF agreed that all patients should go through Triage at Mulago assessment center, and only cases meeting Marburg case definition should be referred to isolation facility. The rest should be given good medical care.
Mpigi
- A probable case admitted on 14 Oct 2014 is being monitored at Mpigi HC IV. Blood sample tested was negative for malaria, brucellosis, and typhoid.
- Turn up of patients at Mpigi HCIV has increased as the health workers also increase following their completion of the 21 days.
- There is urgent need to equip lower level health facilities with information, some PPEs and other supplies to enable them to confidently manage alert cases.
Kasese
- Currently, no patient is admitted in the isolation unit.
- MOH, WHO and Makerere University School of Public Health conducted a training of health workers on VHF preparedness, response and case management and infection prevention and control. Health workers trained were from Kilembe, Bweera and Kagando hospitals and Bukonzo West health sub-District.
Social mobilization
-------------------
Kampala
- Radio spot messages continue to run on 26 local FM radio stations.
- TV spots on Ebola and Marburg on 4 TV stations (WBS, UBC, NTV, NBS)
- Plan is underway to deploy film van in 8 districts of Kampala, Mukono, Wakiso, Mpigi, Ibanda, Kamwengye, Kasese and Bundibugyo, with support from UNICEF.
- The process of printing of IEC materials is ongoing, with support from UNICEF Mpigi.
- Use of community megaphone/community radios was encouraged because it is cheaper and has a wider coverage.
- Sensitization has only been done in Mpigi T/C; scaling up to the rest of the sub counties requires budget support from MOH.
- The CAO will appeal to the DEO to communicate with all the head teachers so that they disseminate messages on Marburg to the school-going children.
- World vision pledged to support another talk show on Saturday [18 Oct 2014] at CBS if technical officers at the district and MOH are available.
- World Vision will also pay for radio spot messages if MOH can prepare and submit them to their office.
- There is still a gap in the IEC materials.
Kasese
- Radio spots and talks shows are ongoing on local FM radios.
Psychosocial Support
----------------------
Kampala
- Psychosocial team is planning to link up with the contact tracing team and provide psychosocial support for contacts identified to be in need of the service.
- The team was requested to prioritize provision of psychosocial support to the health workers in Mengo hospital, especially those that were contacts.
Logistics
------
- Mpigi CAO submitted the district Marburg response budget to MOH.
- VHF Preparedness and Response plan to be presented to Cabinet for resource mobilization for required logistics.
Challenges/Gaps
--------------
- Inaccurate media reports, e.g. Monitor report on 13 Oct 2014, indicating that Uganda has been declared Marburg free could hamper the response activities.
- Some contacts in Kampala leave their homes and switch off their telephones making it difficult for them to be contacted and traced.
- Some contacts travel to other districts and to DRC, posing a risk of spread to other districts and countries in case they fall ill with Marburg.
- Delayed release of funds for district response activities
- Several health workers require training and orientation.
- Shortage of funds for critical response activities
- Fear among health workers in dealing with VHF patients
Planned Activities
-----------------
- A Press conference has been scheduled for 2:30 pm on 15 Oct 2014 by Mpigi district and will involve the RDC, LCV chairman, the CAO and DHO.
- Mobilization of resources for the District Response Plans
- Train health workers in the various health facilities in Kampala on VHF.
- Strengthen surveillance nationwide, especially in Kampala, Kasese, Mpigi, Wakiso, Ibanda, and Kamwenge.
- Continue investigations for the source of exposure for the index case.
- Equip the Kagando Isolation Facility.
- Train and deploy additional contact tracers in Kasese district.
Partners Involved
----------------
Ministry of Health WHO
UNICEF
MSF
KCCA, Kasese District Local Government, Mpigi District Local Government CDC
Uganda Red Cross
Conservation for Public Health
College of Veterinary, Animal Health and Bio Security (COVAB) Global Health Security
World Vision
Uganda Prisons Services
Note: This Situation Report has been developed by the National Task Force. For further clarification, contact Dr. Jane Ruth Aceng (DGHS)/(Chairperson, NTF), 0772664690,
Dr. Francis Adatu (ACHS/ESD) 0772999668,
Dr. Issa Makumbi (Manager, Emergency Operations Centre) 0750996034.
--
Communicated by:
Refaya Ndyamuba
<rndyamuba@gmail.com>
[To reiterate, there appear to be no new confirmed cases but 2 new probable cases, one in Kampala and one in Mpigi. The original report also contains a table, which we are unable to reproduce here, with details of numbers of contacts traced by region. It notes 192 possible contacts, 49 of whom are healthcare workers. Considerable contact tracing is ongoing, since the onset of the (apparent) index case on 11 Sep 2014 and his death on 28 Sep 2014. Today, 15 Oct 2014, marks day 17 since the last possible contact, nearing the extreme end of a 21-day possible incubation period. We await results of laboratory testing with great interest. - Mod.LM
A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/97.]
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- Beiträge: 35199
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Marburg-Fieber in Uganda
MARBURG VIRUS DISEASE - UGANDA (06): UPDATE
*******************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Mon 20 Oct 2014
From: Refaya Ndyamuba <rndyamuba@gmail.com> [edited]
National Marburg hemorrhagic fever outbreak, situation report no 14, as at 18:00 hrs; 20 Oct 2014
--------------------------------------------------------------------
[The situation report includes a table of "Summary Statistics" that is not reproduced here. There is only one confirmed fatal case and all suspected (16) and probable (26) cases have now been discarded. - Mod.LM]
Highlights of the day
---------------------
- The suspect case admitted at Mulago Isolation unit, with history of travel from Sierra Leone, on 18 Oct 2014, tested negative on PCR for Ebola Zaire, Ebola Sudan, CCHF [Crimean-Congo hemorrhagic fever], and RVF [Rift Valley fever], Marburg, and Ebola Bundibugyo on 19 Oct 2014.
- No new case of Marburg disease has been confirmed since detection of the index case, [who] was buried on 30 Sep 2014
Situation update
----------------
Coordination
------------
Kampala:
- NTF [National Task Force] held meeting on 20 Oct 2014, next meeting is scheduled for Wed 22 Oct 2014
- All cadres of health workers will undergo a 3 day intensive training [period] in infection prevention and control (IPC). The training will be supported by MSF [Medecins sans Frontieres] and is scheduled to start on Wed 22 Oct 2014 at Mulago national referral hospital Kampala, districts of Wakiso and Mukono to be brought on board.
- NTF recommended training of traditional healers since a good number of people consult them before going to health facilities
- UNICEF funds for social mobilization will be sent to MOH for disbursement to districts
- IEC [information, education, communication] materials with support from UNICEF were supplied to DHOs [district health officers] according to MOH schedule
Mpigi:
- Funds to support district response activities are still awaited from MOH
- DTF [District Task Force] meeting held on Mon 20 Oct 2014
Kasese:
- DTF meeting was held on Tue 14 Oct 2014 and the next meeting is scheduled on Tue 21 Oct 2014
Epidemiology/surveillance/laboratory
------------------------------------
Kampala:
- No alert received from community on 20 Oct 2014.
- The 3 blood samples form Kole district received by UVRI [Uganda Virus Research Institute] on 19 Oct 2014; laboratory investigation is ongoing.
- 24 out of 24 (100 per cent) were followed up on 20 Oct 2014 and all were reported healthy.
- 17 out 24 contacts completed 21 days of follow up today [20 Oct 2014] and will be dropped from the list on 21 Oct 2014, hence only 7 will remain on the list
- Investigation of source of infection of index case still ongoing
Mpigi:
- The last contact completed 21 days of follow up today [20 Oct 2014] hence will be dropped from the list
- The psychosocial team from the center was requested from the national level to meet and discuss with relatives of the deceased Marburg victim -- the national level should take this up urgently
Kasese:
- 62 of the 72 contacts (86 per cent) were reached on 20 Oct 2014 and none of them was reported to be having symptoms.
Case management
---------------
Kampala:
- The suspect case who was admitted at Mulago Isolation unit on 18 Oct 2014 is reported to be improving on treatment, the repeat blood sample is scheduled to be taken on 21 Oct 2014.
Mpigi:
- No Marburg suspected case on admission today [20 Oct 2014] in Mpigi health facilities
- Patient turn up continues to increase though the community is still skeptical
- Circumcision schedules at Mpigi HCIV [Health Center IV-county level care] have been postponed till the end of the 42 days when the country declares end of Marburg outbreak
Kasese:
- No Marburg suspected case on admission today [20 Oct 2014] in Kasese isolation facility
Social mobilization
-------------------
Kampala:
- Radio spot messages continue to run on 26 local FM radio stations
- TV spots on Ebola and Marburg continue to run on 4 TV stations (WBS, UBC, NTV, NBS)
- IEC materials distribution is ongoing in Kampala with support from UNICEF
Mpigi, Kasese:
- Radio spots and talks shows are ongoing on local FM radios.
Psychosocial support
--------------------
Kampala:
- The team plans to work with case management teams and have cases/suspects counseled in addition to following up other contacts identified by contact tracing teams to be in need of psychosocial support
Mpigi:
- The psychosocial team from the national level has been requested to provide services to the relatives of the deceased Marburg victim in Mpigi district
Logistics
---------
- In Mpigi the laboratory personnel who burnt up all his belongings wants to be compensated if possible; partners have been called upon to support the cause
- Budgets for district response activities are not yet supported
Challenges/gaps
---------------
- The NTF and DTFs cannot execute the planned national and district wide activities due to lack of funding and this has negatively impacted the Marburg control planned activities. These include sensitization of VHTs [village health team workers], training of HWs [health workers], contact tracing, and responding to alert cases among others
Planned activities:
- Take a repeat blood sample from a patient admitted at Mulago isolation facility
- Mobilization of resources for District Response Plans
- Train health workers in the various health facilities in Kampala and neighboring districts on VHF [viral hemorrhagic fevers]
- Strengthen surveillance nationwide, especially in Kampala, Kasese, Mpigi, Wakiso, Ibanda, and Kamwenge
- Continue investigations for the source of exposure for the index case
Partners involved
-----------------
Ministry of Health
WHO
UNICEF
MSF
KCCA [Kampala Capital City Authority], Kasese District Local Government, Mpigi District Local Government
USAID
CDC
Uganda Red Cross
Conservation through Public Health
College of Veterinary, Animal Health and Bio Security (COVAB) [Uganda]
Global Health Security
World Vision
Uganda Prisons Services
Note: This situation report has been developed by the National Task Force. For further clarification contact:
Dr Jane Ruth Aceng (DGHS/director general health services)/chairperson, NTF
Dr Francis Adatu (ACHS/ESD)
Dr Issa Makumbi (manager, Emergency Operations Centre)
--
Refaya Ndyamuba
<rndyamuba@gmail.com>
[ProMED-mail is grateful to the Uganda National Task Force for providing this detailed update. Now more than 21 days (the maximum incubation period) since the death of the only confirmed case with all suspected and probable cases now discarded, it is likely that this outbreak has ended. - Mod.LM
Maps of Uganda can be seen at http://en.wikipedia.org/wiki/Districts_of_Uganda and http://healthmap.org/promed/p/97. - Sr.Tech.Ed.MJ]
*******************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
Date: Mon 20 Oct 2014
From: Refaya Ndyamuba <rndyamuba@gmail.com> [edited]
National Marburg hemorrhagic fever outbreak, situation report no 14, as at 18:00 hrs; 20 Oct 2014
--------------------------------------------------------------------
[The situation report includes a table of "Summary Statistics" that is not reproduced here. There is only one confirmed fatal case and all suspected (16) and probable (26) cases have now been discarded. - Mod.LM]
Highlights of the day
---------------------
- The suspect case admitted at Mulago Isolation unit, with history of travel from Sierra Leone, on 18 Oct 2014, tested negative on PCR for Ebola Zaire, Ebola Sudan, CCHF [Crimean-Congo hemorrhagic fever], and RVF [Rift Valley fever], Marburg, and Ebola Bundibugyo on 19 Oct 2014.
- No new case of Marburg disease has been confirmed since detection of the index case, [who] was buried on 30 Sep 2014
Situation update
----------------
Coordination
------------
Kampala:
- NTF [National Task Force] held meeting on 20 Oct 2014, next meeting is scheduled for Wed 22 Oct 2014
- All cadres of health workers will undergo a 3 day intensive training [period] in infection prevention and control (IPC). The training will be supported by MSF [Medecins sans Frontieres] and is scheduled to start on Wed 22 Oct 2014 at Mulago national referral hospital Kampala, districts of Wakiso and Mukono to be brought on board.
- NTF recommended training of traditional healers since a good number of people consult them before going to health facilities
- UNICEF funds for social mobilization will be sent to MOH for disbursement to districts
- IEC [information, education, communication] materials with support from UNICEF were supplied to DHOs [district health officers] according to MOH schedule
Mpigi:
- Funds to support district response activities are still awaited from MOH
- DTF [District Task Force] meeting held on Mon 20 Oct 2014
Kasese:
- DTF meeting was held on Tue 14 Oct 2014 and the next meeting is scheduled on Tue 21 Oct 2014
Epidemiology/surveillance/laboratory
------------------------------------
Kampala:
- No alert received from community on 20 Oct 2014.
- The 3 blood samples form Kole district received by UVRI [Uganda Virus Research Institute] on 19 Oct 2014; laboratory investigation is ongoing.
- 24 out of 24 (100 per cent) were followed up on 20 Oct 2014 and all were reported healthy.
- 17 out 24 contacts completed 21 days of follow up today [20 Oct 2014] and will be dropped from the list on 21 Oct 2014, hence only 7 will remain on the list
- Investigation of source of infection of index case still ongoing
Mpigi:
- The last contact completed 21 days of follow up today [20 Oct 2014] hence will be dropped from the list
- The psychosocial team from the center was requested from the national level to meet and discuss with relatives of the deceased Marburg victim -- the national level should take this up urgently
Kasese:
- 62 of the 72 contacts (86 per cent) were reached on 20 Oct 2014 and none of them was reported to be having symptoms.
Case management
---------------
Kampala:
- The suspect case who was admitted at Mulago Isolation unit on 18 Oct 2014 is reported to be improving on treatment, the repeat blood sample is scheduled to be taken on 21 Oct 2014.
Mpigi:
- No Marburg suspected case on admission today [20 Oct 2014] in Mpigi health facilities
- Patient turn up continues to increase though the community is still skeptical
- Circumcision schedules at Mpigi HCIV [Health Center IV-county level care] have been postponed till the end of the 42 days when the country declares end of Marburg outbreak
Kasese:
- No Marburg suspected case on admission today [20 Oct 2014] in Kasese isolation facility
Social mobilization
-------------------
Kampala:
- Radio spot messages continue to run on 26 local FM radio stations
- TV spots on Ebola and Marburg continue to run on 4 TV stations (WBS, UBC, NTV, NBS)
- IEC materials distribution is ongoing in Kampala with support from UNICEF
Mpigi, Kasese:
- Radio spots and talks shows are ongoing on local FM radios.
Psychosocial support
--------------------
Kampala:
- The team plans to work with case management teams and have cases/suspects counseled in addition to following up other contacts identified by contact tracing teams to be in need of psychosocial support
Mpigi:
- The psychosocial team from the national level has been requested to provide services to the relatives of the deceased Marburg victim in Mpigi district
Logistics
---------
- In Mpigi the laboratory personnel who burnt up all his belongings wants to be compensated if possible; partners have been called upon to support the cause
- Budgets for district response activities are not yet supported
Challenges/gaps
---------------
- The NTF and DTFs cannot execute the planned national and district wide activities due to lack of funding and this has negatively impacted the Marburg control planned activities. These include sensitization of VHTs [village health team workers], training of HWs [health workers], contact tracing, and responding to alert cases among others
Planned activities:
- Take a repeat blood sample from a patient admitted at Mulago isolation facility
- Mobilization of resources for District Response Plans
- Train health workers in the various health facilities in Kampala and neighboring districts on VHF [viral hemorrhagic fevers]
- Strengthen surveillance nationwide, especially in Kampala, Kasese, Mpigi, Wakiso, Ibanda, and Kamwenge
- Continue investigations for the source of exposure for the index case
Partners involved
-----------------
Ministry of Health
WHO
UNICEF
MSF
KCCA [Kampala Capital City Authority], Kasese District Local Government, Mpigi District Local Government
USAID
CDC
Uganda Red Cross
Conservation through Public Health
College of Veterinary, Animal Health and Bio Security (COVAB) [Uganda]
Global Health Security
World Vision
Uganda Prisons Services
Note: This situation report has been developed by the National Task Force. For further clarification contact:
Dr Jane Ruth Aceng (DGHS/director general health services)/chairperson, NTF
Dr Francis Adatu (ACHS/ESD)
Dr Issa Makumbi (manager, Emergency Operations Centre)
--
Refaya Ndyamuba
<rndyamuba@gmail.com>
[ProMED-mail is grateful to the Uganda National Task Force for providing this detailed update. Now more than 21 days (the maximum incubation period) since the death of the only confirmed case with all suspected and probable cases now discarded, it is likely that this outbreak has ended. - Mod.LM
Maps of Uganda can be seen at http://en.wikipedia.org/wiki/Districts_of_Uganda and http://healthmap.org/promed/p/97. - Sr.Tech.Ed.MJ]
-
Birgitt
- Moderator
- Beiträge: 35199
- Registriert: Di 2. Aug 2005, 22:52
- Wohnort: NRW / Südl. Rheinland
- Kontaktdaten:
Uganda | Queen-Elizabeth-Nationalpark - Marburg-Forschungen in der Python-Cave
Forschende, die die Python-Höhle in Uganda überwachen, haben mit Kameras Tiere und Menschen erfasst, die die von Fledermäusen bevölkerte Höhle besuchen. Der Ort gilt als Hotspot für das Marburg-Virus und erlaubt einen seltenen Einblick in das Risiko zoonotischer Übertragungen ...
Uganda: Forscher filmen Marburg-Hotspot fünf Monate lang – riskante Nähe enthüllt
23.04.2026 - euronews
Uganda's Python Cave reveals how a Marburg virus outbreak could begin
21.04.2026 - phys.org mit längerem Video
Multi-species foraging on a Marburg virus bat reservoir
20.04.2026 - Current Biology, 10.1016/j.cub.2026.02.043
Erstmals wurde in der Python-Höhle in Uganda eine groß angelegte Prädation durch mindestens 14 Arten auf ägyptische Fruchtfledermäuse (ein bekanntes Reservoir für das Filovirus Marburg) beobachtet. Die Wildkameras wurden im Rahmen der langfristigen Leoparden- und Hyänen-Überwachung des „Kyambura Lion Project“ des Volcanoes Safaris Partnership Trust im Queen-Elizabeth-Nationalpark an der Höhle aufgestellt. Das Feldteam besteht aus Bosco Atukwatse, Orin Cornille, Johnson Muhereza, Yahaya Ssemakula und Winfred Nsabimana. Dr. Alex Braczkowski ist der wissenschaftliche Leiter des Projekts ... Übersetzt mit DeepL.com (kostenlose Version) ...
Alexander Braczkowski- Predation on fruit bats at Python Cave filmed by Bosco Atukwatse and VSPT Kyambura Lion Project
Gruß
Birgitt
Uganda: Forscher filmen Marburg-Hotspot fünf Monate lang – riskante Nähe enthüllt
23.04.2026 - euronews
Uganda's Python Cave reveals how a Marburg virus outbreak could begin
21.04.2026 - phys.org mit längerem Video
Multi-species foraging on a Marburg virus bat reservoir
20.04.2026 - Current Biology, 10.1016/j.cub.2026.02.043
Erstmals wurde in der Python-Höhle in Uganda eine groß angelegte Prädation durch mindestens 14 Arten auf ägyptische Fruchtfledermäuse (ein bekanntes Reservoir für das Filovirus Marburg) beobachtet. Die Wildkameras wurden im Rahmen der langfristigen Leoparden- und Hyänen-Überwachung des „Kyambura Lion Project“ des Volcanoes Safaris Partnership Trust im Queen-Elizabeth-Nationalpark an der Höhle aufgestellt. Das Feldteam besteht aus Bosco Atukwatse, Orin Cornille, Johnson Muhereza, Yahaya Ssemakula und Winfred Nsabimana. Dr. Alex Braczkowski ist der wissenschaftliche Leiter des Projekts ... Übersetzt mit DeepL.com (kostenlose Version) ...
Alexander Braczkowski- Predation on fruit bats at Python Cave filmed by Bosco Atukwatse and VSPT Kyambura Lion Project
Gruß
Birgitt
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Birgitt
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- Beiträge: 35199
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Marburg-Fieber in Uganda | Distrikt Kyegegwa
Uganda hat der WHO am Dienstag offiziell gemeldet, dass im Westen des Landes ein Ausbruch der Marburg-Krankheit festgestellt wurde, wie ein Sprecher der in Genf ansässigen Weltgesundheitsorganisation gegenüber STAT erklärte. Diese Entwicklung könnte die Bemühungen zur Eindämmung des bereits drittgrößten Ebola-Ausbruchs, der jemals in Zentralafrika verzeichnet wurde, weiter erschweren. Bei beiden Krankheiten handelt es sich um virale hämorrhagische Fieber. Die ugandische Regierung hat einen Marburg-Ausbruch bislang noch nicht öffentlich bekannt gegeben. Die US-Botschaft in der ugandischen Hauptstadt Kampala gab jedoch am Montag eine Gesundheitswarnung heraus, in der sie mitteilte, dass ihr ein möglicher Marburg-Fall im Land gemeldet worden sei ... Übersetzt mit DeepL.com (kostenlose Version) ...
Marburg outbreak is reported in Uganda, threatening to complicate Ebola response in region
01.07.2026 - STAT news
Auch das AA hat seine Reisehinweise heute um den Hinweis auf den aktuellen Marburg-Ausbruch im Distrikt Kyegegwa erweitert.
Gruß
Birgitt
Marburg outbreak is reported in Uganda, threatening to complicate Ebola response in region
01.07.2026 - STAT news
Auch das AA hat seine Reisehinweise heute um den Hinweis auf den aktuellen Marburg-Ausbruch im Distrikt Kyegegwa erweitert.
- Karte: OpenStreetMap
Gruß
Birgitt
